scispace - formally typeset
Search or ask a question

Showing papers in "Journal of Critical Care in 2000"


Journal ArticleDOI
TL;DR: The anabolic agent, oxandrolone, significantly decreased weight loss and net nitrogen loss and increased donor site wound healing compared with placebo controls and there were no complications with the use of ox androlone.

146 citations


Journal ArticleDOI
TL;DR: VTE prophylaxis was underprescribed, and VTE diagnostic tests were infrequent, but several ICU-acquired risk factors for VTE were documented in this medical-surgical ICU.

112 citations


Journal ArticleDOI
TL;DR: The results indicate that, in addition to a history of diabetes or alcoholism, patients with DKA and AKA differ in their metabolic parameters more than in their hormonal profile.

98 citations


Journal ArticleDOI
TL;DR: A diverse spectrum of both gram-positive and gram-negative pathogens were implicated in patients with community-acquired pneumonia presenting in septic shock, necessitating broad spectrum empiric antimicrobial coverage.

78 citations


Journal ArticleDOI
TL;DR: PICU patients required higher doses of vancomycin than are typically prescribed to achieve conventionally accepted peak and trough vancomYcin serum concentrations and therefore may negate the need to obtain routine peak concentrations.

43 citations


Journal ArticleDOI
TL;DR: It is concluded that PARS activation plays an important role in the changes of lung mechanics associated with LPS-induced acute lung injury but had no role in vascular failure.

35 citations


Journal ArticleDOI
TL;DR: Early noninvasive monitoring in the emergency department, operating room, and ICU showed reduced cardiac and tissue perfusion functions in patients who subsequently developed ARDS and these patterns were more pronounced in the ARDS patients who died; these patterns may serve as early warning of ARDS.

34 citations


Journal ArticleDOI
TL;DR: The mean ionized magnesium (IMg+2) relationship to total magnesium (TMg) cannot be predicted before the supplementation with the available technology and should be followed independently.

22 citations


Journal ArticleDOI
TL;DR: There were no advantages in weaning outcome by the addition of a 1-hour T-piece trial compared with prompt extubation at PSmin and the weaning success rate and the reintubation rate were similar for the intervention and control groups.

21 citations


Journal ArticleDOI
TL;DR: In this setting, mortality remained constant from 1985 to 1995 among ARDS trauma patients but not among nontrauma ARDS patients because of the new case-mix of the latter population, which now includes HIV and other immunodepressed patients.

19 citations


Journal ArticleDOI
TL;DR: Patients with nonpulmonary organ failure were significantly less likely to improve on HFOV and had a significantly higher mortality than patients with isolated respiratory failure, and children who do not improve onHFOV appear to reach a plateau in oxygenation indices after 3 days of HFOv.

Journal ArticleDOI
TL;DR: It is likely that constitutive NOS is implicated in immediate cardiac, carotid, mesenteric, and renal vascular changes, whereas inducible NOS accounted for delayed responses in hepatic and coronary circulation.

Journal ArticleDOI
TL;DR: Findings suggest that a lack of increase in the production of the cGMP may account for the pulmonary hypertension seen in air embolism-induced ALI, and a small increase in cG MP levels after the MAE may reflect the more severe hemodynamic derangement in this setting.

Journal ArticleDOI
TL;DR: The results suggest that IPC has the effect of improving peripheral circulation, which supports the use of IPC to prevent deep venous thrombosis.

Journal ArticleDOI
TL;DR: The results indicate that myocardial dysfunction in sepsis is frequency dependent, and that the mechanism is most likely caused by inhibition of SR calcium release owing to blockade of the ryanodine channel.

Journal ArticleDOI
TL;DR: Time-weighted nursing demand is a better predictor than midnight census of nursing supply in an ICU as a calculation of need for nursing staff with the actual number of nurses who were required to staff the ICU.

Journal ArticleDOI
TL;DR: An increase in circulating heparinoid activity significantly contributes to the hemostatic disorder associated with hepatoenteric ischemia-reperfusion in rabbits.

Journal ArticleDOI
TL;DR: Investigation of whether the epidural pressure (EPIP) can be monitored for a long period of time using the continuous epidural infusion via the lower thorax allows stable monitoring of the EPIP over a longperiod of time.

Journal ArticleDOI
TL;DR: PLV shows dose-dependent increase in oxygenation with PEEP and may reduce lung damage associated with mechanical ventilation and may be reduced by PLV.

Journal ArticleDOI
TL;DR: Results indicate that critically ill mechanically ventilated patients show improved respiratory mechanics with decelerating inspiratory waveform that may have beneficial clinical implication.

Journal ArticleDOI
TL;DR: DETANONOate significantly decreased hemostatic function in vitro in a dose-dependent fashion but did not significantly affect hemostatics function in vivo.

Journal ArticleDOI
TL;DR: The results indicate that amrinone during an early stage of sepsis is of limited value and attenuates mucosal hypoperfusion but contributes to systemic hypotension.

Journal ArticleDOI
TL;DR: Findings suggest that during the early stages of mechanical ventilation with acute respiratory failure, hemodynamically significant cardiac arrhythmias are directly associated with tachycardia, initial MAP, and, inversely, the initial use of pressure-controlled ventilation.

Journal ArticleDOI
TL;DR: A locally high concentration of prostaglandin I2, at least in part, may produce selectivity of vasodilation in the pulmonary vasculature.

Journal ArticleDOI
TL;DR: Serum sFAsL decreases after surgery, whereas intra-abdominal or cerebrospinal sFasL increases, although sFAS in each site does not change, suggesting redistribution of activated lymphocytes into local surgical wounds and induction of apoptosis in this site.