Showing papers in "Journal of Lipid Research in 1969"

TL;DR: Oleic acid has a partition coefficient, upper phase/lower phase, of 1.9 (22 degrees C) in the liquid-liquid partition system described herein, and can be quantitatively removed from mixtures of triglyceride and partial glycerides by means of this partition system under conditions resembling those in a lipase assay.

TL;DR: In general, palmitate and palmitoleate were bound more tightly than oleate, linoleate, stearate, or myristate, and muchMore tightly than laurate.

TL;DR: The size, number, and rate of formation of mature adipocytes were studied in the epididymal pads and retroperitoneal adipose depots of the Sprague-Dawley rat and the concept of a fixed number of maturity adipocytes in the adult organism may be of central importance in caloric and metabolic equilibrium.

TL;DR: The phospholipid composition of platelets and subcellular fractions was found to differ only in that granules had a lower percentage of lecithin, but the basic lipid composition of the granules, membranes, and platelets was similar.

TL;DR: Estimates of daily synthesis of cholesterol in man are estimated by measuring the excretion of cholesterol and its conversion products during periods of controlled sterol intake (sterol balance method), using isotopic or chromatographic procedures (or a combination of the two).

TL;DR: It is demonstrated that feedback control by dietary cholesterol does occur in man and there are important differences between man and various laboratory animals in regard to the interaction of absorption and synthesis as factors controlling the size of tissue pools of cholesterol.

TL;DR: The feedback mechanism was demonstrated in two kinds of experiments where rats with bile fistulas were infused intraduodenally with sodium taurocholate and the rate of infusion exceeded 10 mg per 100 g rat per hr, and bile acid secretion returned to the low levels observed in intact rats.

TL;DR: The concentrations of lysophosphatidylcholine, which are higher in atherosclerotic than in control aortic tissues, could be a factor controlling rates of fatty acid incorporation into phosphatidylethanolamine.

TL;DR: Evidence is provided for the mutual role of the protein and lipids in determining the structure, and perhaps the immunological specificity, of serum lipoproteins in Sprague-Dawley rats.

TL;DR: The results of these laboratory experiments indicate that 1 ug-1g of PG can be purified by chromatographic methods with little or no loss due to irreversible adsorption or rearrangement if proper precautions and solvent systems are used.

TL;DR: N-Hydroxysuccinimide esters of long-chain fatty acids have been used to synthesize the CoA and thioglycolic acid thiol ester of palmitic and 3-ketopalmitic acids in high yield and with a minimum of untoward side reactions.

TL;DR: The results indicate that the two desaturases are distinct and are inducible in response to different substances.

TL;DR: For these portions of the lipoprotein spectrum, the increase in surface: volume ratio as particle size decreases is approximately compensated for by an increase in the weight percentage of protein.

TL;DR: The combination of ORD and UV affords a nondestructive assay which can determine the relative amounts of E-, A-, and B-type prostaglandins with as little as 1-2 micro g of material.

TL;DR: The present experiments were undertaken to explore what information could be derived from fecal analysis after a single feeding of meals containing labeled cholesterol, and it was found that the plant sterol &sitosterol is absorbed from the human intestine.

TL;DR: It was concluded that the lipoproteins in the Golgi apparatus are the precursors of plasma very low density lipoproteinins in blood plasma.

TL;DR: The difference in specific radioactivity of (14)C-ethanolamine-labeled endogenous mitochondrial phospholipid before and after incubation indicates that a fraction of mitochondrial phosphatidyl ethanolamine is hydrolyzed more rapidly than the mitochondrialospholipids as a whole.

TL;DR: The different rates of turnover and incorporation of radioactivity into different parts of the lipids suggest that exchange reactions may be important to phospholipid metabolism.

TL;DR: The nonpolar (acetone-soluble) lipids of the extremely halophilic bacterium, Halobacterium cutirubrum, were found to consist of red carotenoid pigments and squalenes with a small amount of a vitamin K-type quinone, identified as menaquinone-8 (MK-8).

TL;DR: The concentration of the lipid that accumulates in the tissues in Fabry's disease is elevated in plasma but not in red cells, whereas in Gaucher's disease the accumulating lipid (glucosyl ceramide) is raised in both plasma and red cells.

TL;DR: No significant correlation was found between the amount of coprosterols and the total amount of neutral sterols excreted by the conventional rats, which suggests that bacterial reduction of cholesterol is not an important mechanism of increasing neutral sterol excretion of conventional rats as compared to germfree rats.

TL;DR: The findings indicate that when post-heparin lipolytic activity is measured for the purpose of detecting TGL deficiency, it may be necessary to perform the assay with a substrate free from partial glycerides.

TL;DR: The m/e values of these fragments can be used to determine unequivocally the structures of the long-chain base and fatty acid of a ceramide derived from a sphingolipid.

TL;DR: The finding of phosphosphingolipids in bacteria is exceedingly rare and to the authors' knowledge ceramide phosphorylglycerol has not been previously found in nature.

TL;DR: The deposition of hepatic triglycerides produced by the feeding of deficient diets is markedly potentiated by ethanol; the triglyceride fatty acids accumulated under these conditions appear to originate, for the most part, not from mobilization of depot fat, but from endogenous synthesis.

TL;DR: The galactolipid synthesis is quite resistant to elevated temperature; maximal incorporation of galactose from UDP-galactose was observed at 45 degrees C and the proportion of monogalactosyl diglyceride was greater at the higher temperatures.

TL;DR: Sphingomyelins from human blood plasma have been converted into ceramides by enzymatic hydrolysis with phospholipase C and fractionated by thin-layer chromatography on silica gel containing silver nitrate.

TL;DR: Ascorbic acid functioned as a true catalyst, i.e., it accelerated the reaction but it was not oxidized simultaneously with the linoleate, and it is proposed that the dehydroascorbic acid radical initiates the linolesate oxidation reaction.

TL;DR: The temperature dependence of spontaneous, fatty acid-induced, or CaCl(2)-induced swelling suggested that enzymatic activities are responsible for swelling, although swelling due to contaminating lysosomes cannot be excluded entirely.

TL;DR: In this paper, the ethanolamine phosphoglycerides were obtained from lipid extracts of ox and mouse brains by pre- parative thin-layer chromatography. But the results showed that the side chains from the 1-position of these two ethanolamines are different in chain length and unsaturation as well as in chemical bonding.