Showing papers in "Journal of the Neurological Sciences in 2004"
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TL;DR: Visual and auditory cues improved gait performance in patients with PD, but they did so in different ways and the simultaneous use of auditory and visual cues did not improve gait significantly more than each cue alone.
317 citations
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TL;DR: Low-level aerobic training in MS improves not only quality of life but also coordinative function and physical fitness and disease-specific quality oflife significantly increased in the training group.
303 citations
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TL;DR: The neuropathological substrates of VaD also need to be better defined to impact on preventative and treatment strategies and are critical for selective recruitment to clinical trials.
266 citations
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TL;DR: The concept of VCI could be more useful if it were to be limited to cases of vascular MCI without dementia, by analogy with the concept of amnestic MCI, currently considered the earliest clinically diagnosable stage of Alzheimer disease (AD).
261 citations
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TL;DR: High-frequency rTMS over left DLP FC was able to ameliorate chronic migraine, in agreement with the suggested role of DLPFC in pain control.
233 citations
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TL;DR: An estimate of the prevalence of the disease, verifying the association with HT and investigating the pathogenetic role of anti-thyroid antibodies are sought, and the intrathecal synthesis of autoantibodies is a distinctive marker of this elusive condition.
228 citations
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TL;DR: The study shows that white matter lesions are common and are an independent risk factor for dementia using multivariable analysis, and examines white matter pathology in this cohort as a potential manifestation of small-vessel disease in the ageing brain.
222 citations
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TL;DR: The final model of PD risk suggests that occupational, environmental lifestyle and, likely, genetic factors, individually and collectively, play a significant role in the etiology of the disease.
212 citations
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TL;DR: Small fiber neuropathy is a neuropathy selectively involving small diameter myelinated and unmyelinated nerve fibers and typically presents with peripheral pain and/or symptoms of autonomic dysfunction.
195 citations
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TL;DR: The proposed theory is consistent with the neuropathological findings in syringomyelia and with the pressure and composition of syrinx fluid and explains the poorly understood presentation of foramen magnum meningiomas with symptoms of a mid- to low-cervical myelopathy.
184 citations
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TL;DR: The concept of Vascular Cognitive Impairment (VCI) encompasses patients across the entire continuum of cognitive impairment resulting from cerebrovascular disease (CVD), ranging from high-risk patients with no frank cognitive deficit (the "brain-at-risk" stage) through vascular dementia (VaD).
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TL;DR: The results of this study show that ALCAR is better tolerated and more effective than amantadine for the treatment of MS-related fatigue.
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TL;DR: Improved wrist extension motor capabilities findings support EMG-triggered neuromuscular stimulation as an effective poststroke protocol.
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TL;DR: This trial does not support the efficacy of specific memory and attention retraining in MS and indicates changes in depression and health-related quality of life.
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TL;DR: A slight but significant elevation in %CoQ-10 was observed in PD patients when compared with age/gender-matched normal subjects, suggesting elevated systemic oxidative stress inPD patients.
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TL;DR: It is suggested that systemic chemotherapy alone or in combination with other therapeutic modalities may improve outcome in patients with subarachnoid tumor cell deposits detectable by neuroimaging.
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TL;DR: In conclusion, musical hallucinations are a phenomenon with heterogeneous clinical and pathophysiological backgrounds, and anticonvulsant and antidepressive substances were reported to be effective most consistently.
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TL;DR: Edaravone was associated with delayed evolution of infarcts and edema in patients with severe carotid-territorial stroke and decreased mortality during the acute stage and did not significantly improve functional outcome among the surviving patients.
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TL;DR: Protein S100B may serve as a monitoring parameter in acute ischemic stroke, especially with respect to the neurovascular status, and was highly correlated with the severity of the corresponding neurological deficit as well as with the final infarct volume.
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TL;DR: Results showed that prefrontal cortex, rather than striatum, had the greatest number of changes in the two typical TS cases, including increases for D2, DAT, VAMP-2, and alpha-2A.
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TL;DR: Data provide compelling evidence for a role for the Hfe mutation in etiopathogenesis of ALS and warrant further investigation.
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TL;DR: Acute stroke mortality related to increasing serum-cortisol levels, and s- cortisol was associated with stroke severity and markers reflecting stroke severity.
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TL;DR: It was found that clinical features, including time to maximal diplopic symptoms, were not predictive of etiology and neuroimaging procedures may have a role in the initial evaluation of patients 50 years of age or older with acute ocular motor mononeuropathies.
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TL;DR: GABS is an easy-to-use comprehensive clinical scale with high intra-rater and internal item reliability and is expected to have a particular utility in clinical trials designed to modify functional impairment associated with abnormalities in gait and balance.
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TL;DR: The results suggest that the early use of steroids may decrease progression of ocular to generalized myasthenia gravis and the decision to use steroids should be considered early in the course of patients diagnosed with ocular myastenia Gravis.
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TL;DR: Snoring was the most important risk factor associated with EDS and RLS was more frequent in patients with longer duration of illness, and a marginal association between motor dysfunction and EDS was observed.
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TL;DR: It is demonstrated that acute rTMS treatment of the frontal brain affects the DAergic neuronal system in the rat dorsolateral striatum, and may have therapeutic implications for Parkinson's disease.
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TL;DR: Pretreatment with statins seems to be associated with reduced clinical severity in patients with acute ischemic cerebrovascular events, particularly in patientsWith diabetes, a significant interaction between the presence of diabetes and the effect of pretreatment withStatins on stroke outcome is found.
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TL;DR: Obese females in metropolitan Detroit would benefit from routine eye evaluations to avoid potential visual loss related to papilledema and an increased number of asymptomatic patients after routine ophthalmic examination are reported.
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TL;DR: Hcy increases the risk of micro- and macrovascular disease as well as brain atrophy, and thereby impaired cognition, and therefore remediation of high Hcy levels should begin early in life.