Showing papers in "Neurologic Clinics in 1985"

TL;DR: Surgery for epilepsy is currently practiced at several centers in this country and abroad, with great need for more such centers and more education about this treatment as estimates indicate 100,000 patients in the United States at this time could benefit from such procedures.

TL;DR: An early and accurate diagnosis, coupled with improvement in the surgical approach, offers a much better prognosis for patients with thoracic disk herniation.

TL;DR: Subacute sclerosing panencephalitis is a neurodegenerative disease of childhood that is due to a persistent measles infection that is coexistent with the decline in natural measles infection.

TL;DR: Migraine is a hereditary disorder afflicting 5 per cent of school-age children, and symptoms are protean and may not include headache.

TL;DR: This article covers chemotherapy of malignant astrocytomas, ependymoma, and medulloblastoma and the future direction of anticancer drugs is discussed.

TL;DR: Careful diagnostic evaluation of patients with cancer and neurologic symptoms often indicates effective therapy.

TL;DR: The myelopathy that may accompany cervical spondylosis is examined with reference to pathogenesis, clinical features, investigations, and treatment.

TL;DR: The pathophysiologic processes underlying plexus lesions and their recognition by electromyographic examination are detailed and the nerve conduction studies most helpful for localization of plexopathies are discussed.

TL;DR: Combinations of needle electromyography, nerve conduction studies, and other techniques can not only confirm the diagnosis or identify the presence of unsuspected disease, but can also provide clues to the rate of progression and prognosis.

TL;DR: This review deals with electromyographic criteria that distinguish between weakness and wasting due to disease of the muscle fiber or secondary to denervation.

TL;DR: The EEG may reveal that the alteration in consciousness is due to continual epileptic activity without motor manifestations (nonconvulsive status) that had not been suspected, and certain patterns have prognostic implications.

TL;DR: Electrophysiology assesses function and should be considered complementary to, not as competing with, myelography, which assesses structure, while electromyography, being devoid of morbidity and significant side effects, should precede invasive radiology:Myelography and contrast-enhanced computerized tomography (CT).

TL;DR: Oncogenes may exert their transforming activity by encoding proteins that mimic the function of the normal regulatory factors along the mitogenic pathway, growth factors, their receptors or elements along the postreceptor signaling system.

TL;DR: Diffuse astrocytomas of the cerebrum, cerebellum, brain stem, and spinal cord are classified into three groups according to the degree of tumor anaplasia, and it remains controversial whether these tumors should be classified as a single entity with the potential for differentiation along different cell lines, or whether they should be retained as specific entities.

TL;DR: As I have indicated in the foregoing discussion, there are several syndromes that with various degrees of proof seem to be caused by unilateral vascular compression of a cranial nerve at the brain stem.

TL;DR: The author presents a discussion of the role of radical resection and reoperation in the treatment of patients with malignant brain tumors and the principles of the surgical method are detailed.

TL;DR: As diagnostic techniques improve, fewer diagnoses of childhood stroke remain in the category of acute infantile hemiplegia, which is most important, because specific therapy, when available, of underlying conditions can prevent recurrent strokes.

TL;DR: This article reviews current morbidity and mortality statistics for the major classes of primary brain tumors including malignant astrocytoma, glioblastoma, low-grade astro Cystic fibrosis, oligodendroglioma, meningioma, and other benign tumors and metastatic tumors.

TL;DR: Evaluation of biopsied malignant gliomas by karyotyping has demonstrated that subgroups of them are characterized by specific numerical and structural deviations, which may prove useful in predicting prognosis or responsiveness to specific therapeutic regimens.

TL;DR: The authors discuss the feasibility of treatment of malignant tumors with brachytherapy and its present day use, and future directions are detailed.

TL;DR: As brain tumors evade immunosurveillance through active participation in inducing tumor-specific immunosuppression, successful immunotherapy will be best achieved in patients with a slight or moderate Immunosuppressive state.

TL;DR: It is demonstrated that drug delivery to brain tumors is a function of both drug properties and tumor properties and that both must be considered in planning chemotherapeutic strategies.

TL;DR: Phase II trials using the drugs effective in these models may identify active agents that will ultimately increase survival when used in an adjuvant setting, and in vitro and in vivo models of human medulloblastoma using the medullo-derived cell lines TE-671 and D283 Med may allow such an approach.

TL;DR: The pathogenesis and management of hypoxic-ischemic encephalopathy in the term infant is reviewed including changes in cerebral blood flow, brain swelling, carbohydrate status, alterations in ion homeostasis, and synaptic activity.

TL;DR: This overview discusses diagnostic accuracy, postoperative care, radiation therapy, reoperation, clinical trials, and care of the dying patient.

TL;DR: The ultrasound scanner, as developed for neurosurgery, will become another instrument in the neurosurgeon's armamentarium and guide the instrumentation of lesions of the brain and spinal cord.

TL;DR: This article provides a review for the nonradiotherapist of the place of conventional external beam radiotherapy in neuro-oncology.

TL;DR: This article discusses intracranial aneurysms and subarachnoid hemorrhage in terms of prevalence, etiology, pathology, pathophysiology, and clinical presentation.

TL;DR: The syndrome of a lumbar spinal and lateral recess stenosis is characterized by pain and a variety of paresthetic symptoms occurring principally when the patient stands or walks, and a myelogram is in order to establish a definitive diagnosis.

TL;DR: The technique of repetitive nerve stimulation was developed as a means of confirming a diagnosis of MG and has identified other disorders of neuromuscular transmission such as LEMS, infantile botulism, and several forms of congenital myasthenia.