Showing papers in "Phytochemistry in 2022"

TL;DR: In this paper , the isolated new terpenoids from plant endophytic fungi, their hosts, as well as biological activities, from January 2011 until the end of 2020 are reviewed.

TL;DR: A comprehensive overview of stilbenes' botanical sources, chemistry, biosynthetic pathways, pharmacology, and clinical applications and challenges based on up-to-date data is provided in this paper .

TL;DR: In this article , six undescribed germacrane-type sesquiterpene lactones, namely scaberxones A-F, along with a known analog were obtained and characterized from Elephantopus scaber L. Their structures were unequivocally assigned by detailed spectroscopic analyses, NMR and ECD spectral calculations, and computer-assisted structure elucidation.

TL;DR: In this article, the authors used a gnotobiotic system to investigate the effects of the endophytic fungus Cladosporium tenuissimum DF11 on tanshinone biosynthesis in S. miltiorrhiza roots.

TL;DR: In this article , five undescribed CPA-type indole alkaloids, aspergillines F-J, and cyclopiamide E, were obtained from the Nicotiana tabacum-derived fungus Aspergillus versicolor.

TL;DR: In this paper , the authors used a gnotobiotic system to investigate the effects of the endophytic fungus Cladosporium tenuissimum DF11 on tanshinone biosynthesis in S. miltiorrhiza roots.

TL;DR: A molecular networking-guided study on the Daphne genkwa Sieb led to the isolation of twelve daphnane-type diterpenoids including four undescribed compounds, yuanhuakines A-D as mentioned in this paper .

TL;DR: In this paper , the first step of primary antioxidant action for phenolic OH groups of benzoic and cinnamic acid derivatives, and their carboxylate anions were studied.

TL;DR: In this paper , the potential crosstalk between Nrf2 and NF-κB and the upstream regulators of NRF2 and review the literature on the antioxidant and anti-inflammatory effects of dietary phytochemicals that can activate these defence systems.

TL;DR: Berberine alkaloids belong to the class of isoquinoline alkaloid that have been shown to possess anticancer potential, berberine exhibits inhibitory effects on breast cancer development as mentioned in this paper .

TL;DR: A review of chemical, biosynthesis, and biological studies on terpenoids discovered from the genus Aspergillus, including mono-, sesqui-, di-, sester-, tri-, and meroterpenoids, is presented in this article .

TL;DR: A review of chemical, biosynthesis, and biological studies on terpenoids discovered from the genus Aspergillus, including mono-, sesqui-, di-, sester-, tri-, and meroterpenoids, is presented in this article.

TL;DR: A comprehensive review of polyacetylenes from herbal medicine is presented in this paper , which reconstructs data concerning the occurrence, pharmacology, toxicology and pharmacokinetics with a view to backing up their curative potential and healthcare properties (2014-2021).

TL;DR: In this paper , a review of the pharmacological activities of carvone in experimental models in vitro and in vivo is presented, where two independent reviewers performed the selection of articles using Rayyan application, extracted the relevant data and assessed the methodological quality of the selected studies using Syrcle's risk of bias tool.

TL;DR: In this paper , the anti-cancer, anti-oxidant, and anti-inflammatory properties of Thymoquinone (TQ) have been investigated for its numerous health benefits, including anti-proliferation, cell cycle arrest, apoptosis induction, ROS production, antimetastasis and antiangiogenesis.

TL;DR: In this article , the first investigation of Hedera rhombea bean fruit was presented, which led to the isolation of six undescribed compounds including two megastigmane glucosides, two rare 1,4-dioxane neolignanes, and two quinic acid derivatives, together with 26 known compounds.

TL;DR: In this paper , four undescribed isobenzofuranones, namely sporulactones A, D, E and F, together with eight known analogs were isolated from the kiwi endophytic fungus Paraphaeosphaeria sporulosa.

TL;DR: In this paper , a review summarizes the research work on Astragalus and their biologically active constituents as potential candidates for the protection against and treatment of neurodegenerative and neuropsychiatric disorders to show the potential efficacy of Astragsalus sp. and its active ingredients in treating some neurological diseases.

TL;DR: In this paper , the analysis of the metabolites from Arthrinium arundinis DJ-13 grown in solid medium revealed six undescribed cytochalasans, arundisins A-F and twelve known compounds.

TL;DR: In this paper , a literature review summarizes the current knowledge on the interaction of non-isothiocyanate products with fungi, including compounds including glucosinolates and their biosynthesis precursors.

TL;DR: The analysis of the metabolites from Arthrinium arundinis DJ-13 grown in solid medium revealed six undescribed cytochalasans, arundisins A-F and twelve known compounds.

TL;DR: Cucurbitacin C analogues including seven undescribed ones have been isolated from the bitter leaves of cucumber, in which six compounds showed growth inhibition capabilities against tumor cell lines HepG2, A549, DU145 and HCT116 as mentioned in this paper .

TL;DR: The Gretchen Hagen 3 (GH3) genes encoding proteins belonging to the ANL superfamily are widespread in the plant kingdom as discussed by the authors , which are cytosolic, acidic amidosynthetases of the firefly luciferase group that conjugate auxins, jasmonates, and benzoate derivatives to a wide group of amino acids.

TL;DR: In this article , seven previously undescribed cadinane sesquiterpenoids, albocinnamins A, G and D, were isolated from the fungus Antrodiella Albocinnamomea and their structures with absolute configurations were elucidated on the basis of extensive spectroscopic methods, as well as single crystal X-ray diffraction.

TL;DR: In this paper , 14 undescribed phloroglucinol-meroterpenoids, namely eucalypcamals A-N, were isolated from a CH2Cl2 extract of the leaves of Eucalyptus camaldulensis Dehnh.

TL;DR: Wang et al. as discussed by the authors investigated the national compound library of traditional Chinese medicines (NCLTCMs), a phytochemical library comprising over 9000 TCM-derived compounds and found nine natural biflavones were effective PLpro inhibitors with IC50 values ranging from 9.5 to 43.2 μM.

TL;DR: In this paper , the structures and absolute configurations of those undescribed compounds were established by NMR spectroscopy data, HRESIMS analyses and electronic circular dichroism (ECD) analyses.

TL;DR: In this article , three different chemometric-based classification models were constructed using three sets of chemical profiles, and the combined cannabinoid-and-terpene PLS-DA profile had cross-validation and prediction misclassification errors of 4% and 0%, respectively.

TL;DR: Wang et al. as mentioned in this paper investigated the national compound library of traditional Chinese medicines (NCLTCMs), a phytochemical library comprising over 9000 TCM-derived compounds and found nine natural biflavones were effective PLpro inhibitors with IC50 values ranging from 9.5 to 43.2 μM.

TL;DR: In this paper , the authors quantified and compared the amount of stevioside and rebaudioside A in two of the most used S. rebaudiana cultivars, Morita II and Criolla.