Showing papers in "Phytomedicine in 2007"

TL;DR: This article aims to provide a comprehensive literature survey of plants that have been tested for AChE inhibitory activity and reports numerous phytoconstituents and promising plant species as A ChE inhibitors.

TL;DR: The results of this experimental study indicate that cinnamaldehyde possesses hypoglycemic and hypolipidemic effects in STZ-induced diabetic rats.

TL;DR: Testing the anti-inflammatory activity of compounds isolated from ginger rhizome demonstrates that compounds found in ginger are capable of inhibiting PGE(2) production and that they may act at several sites.

TL;DR: The combination of Norfloxacin with either P. graveolens essential oil, or with some of the main components of this latter, in the treatment of infections caused by some bacterial species is likely to reduce the minimum effective dose of Nor FLXacin thus minimizing the side effects of the antibiotic.

TL;DR: TQ and NSO may have protective effects on lipid peroxidation process during IRI in rat hippocampus, suggesting that Nigella sativa oil and thymoquinone may prevent oxidative injury in various models.

TL;DR: It is concluded that due to their antimicrobial effects some of the plant extracts may be used for the topical treatment of skin disorders like acne vulgaris and seborrhoic eczema.

TL;DR: The data suggest that RSVL stimulates HBMSCs proliferation and osteoblastic differentiation through an ER-dependent mechanism and coupling to ERK1/2 activation.

TL;DR: It is demonstrated that betanin induces apoptosis in K562 cells through the intrinsic pathway and is mediated by the release of cytochrome c from mitochondria into the cytosol, and PARP cleavage.

TL;DR: The results suggest that SM may to protect the SNC by oxidative damage for its ability to prevent lipid peroxidation and replenishing the GSH levels.

TL;DR: The results show that the extract of T. catappa and its antioxidant, corilagin are protective against GalN/LPS-induced liver injury through suppression of oxidative stress and apoptosis.

TL;DR: The hypothesis that b-sitosterol is an effective apoptosis-promoting agent and that incorporation of more phytosterols in the diet may serve a preventive measure for breast cancer is supported.

TL;DR: It is demonstrated that safranal could exert anticonvulsant activity in the PTZ model and this effect may be mediated, at least partly, through GABA(A)-benzodiazepine receptor complex.

TL;DR: The application of the "-omic-" technologies may lead to a change of paradigms towards the application of complex mixtures in medicine and open the new field of phytogenomics, -proteomics and -metabolomics.

TL;DR: Abietane diterpenoids: salvipisone, aethiopinone, 1-oxoaethiop inone and ferruginol were shown to be bacteriostatic as well as bacteriocidal for the cultures of S. aureus and S. epidermidis strains, regardless of their antibiotic susceptibility profile.

TL;DR: The acetylcholine-induced vasorelaxant activity was significantly decreased in cholesterol-fed animals and could be restored to that of normal values by seed oil administration, suggesting that supercritical CO(2) extracted SBT seed oil has significant anti-atherogenic and cardioprotective activity.

TL;DR: The findings presented here suggest that CMG induces an anoikis form of cell death in HCT116 colon cancer cells that includes events associated with caspase-dependent pathways and might be developed into a chemotherapeutic agent for the treatment of human colon and other cancers.

TL;DR: Together, these experiments suggest that lavender oil does have anxiolytic effects in the open field, but that a sedative effect can also occur at the highest doses.

TL;DR: With neonatal-streptozotocin diabetic rats, paeonol (200 and 400mg/kgbody wt.) was found to improve oral glucose tolerance in vivo, the first report on the anti-diabetic effect of pae onol.

TL;DR: Shenge exerts significant cardioprotective effects against acute ischemic myocardial injury in rats, likely through its antioxidant and anti-lipid peroxidation properties, and thus may be an effective and promising medicine for both prophylaxis and treatment of ischeic heart disease.

TL;DR: This study investigated the pharmacokinetic properties of crocin following oral administration in rats to indicate that orally administered crocin is not absorbed either after a single dose or repeated doses, and that the intestinal tract serves as an important site for crocin hydrolysis.

TL;DR: A small number of randomised controlled studies indicate that a proprietary methanolic extract is effective in improving BPH complaints, however, the significance and magnitude of the effect remains to be established in further confirmatory studies before nettle root treatment may be accepted in the guidelines for BPH treatment.

TL;DR: It is suggested that EGCG stimulates human hair growth through these dual proliferative and anti-apoptotic effects on DPCs.

TL;DR: Thirty aqueous and ethanolic extracts from 13 congolese plants were evaluated for their antidrepanocytary activity, suggesting a possible correlation between the chemical composition of these plants and their uses in traditional medicine.

TL;DR: The present study reports the neutralization of viper and cobra venom by beta-sitosterol and stigmasterol isolated from the root extract of P. indica Less and suggests that beta- sitosterol or stig masterol may play an important role, along with antiserum, in neutralizing snake venom-induced actions.

TL;DR: Functional and functional bioassays provide convincing support for the improvement of immune functions at various levels, hence, validating the medicinal uses of EPs 7630.

TL;DR: The results suggest that isolation and biological characterization of estrogenic compounds in traditionally used medicinal plants could be a first step in better assessing further (e.g. in vivo) tests of nutraceutical and pharmacological strategies based on phytoestrogens.

TL;DR: Action suggests that mitraphylline is a new and promising agent in the treatment of human neuroblastoma and glioma, and the anti-tumoral effects of its pentacyclic alkaloid mit graphylline were investigated.

TL;DR: There was a steady improvement in CD symptoms in 18 patients who received wormwood in spite of tapering of steroids as shown by CDA-Index, IBDQ, HAMD, and VAS, which strongly suggest that wormwood has a steroid sparing effect.

TL;DR: It is shown that PIP presents significant anxiolytic and antidepressant activities, making this drug potentially useful in anxiety and depression.

TL;DR: Curcuminoids at this dose were well tolerated and the results suggest that for future studies a larger sample size, a higher dose and/or longer duration of curcuminoid administration should be considered; however, for the next step, an RCT of a shorter duration, using a higher doses of cur cuminoids, and without an initial course of prednisone should be consideration.