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Panayotis Pantazis
Researcher at Brown University
Publications - 28
Citations - 2001
Panayotis Pantazis is an academic researcher from Brown University. The author has contributed to research in topics: Apoptosis & Nitrocamptothecin. The author has an hindex of 16, co-authored 28 publications receiving 1929 citations. Previous affiliations of Panayotis Pantazis include University of Oklahoma Health Sciences Center & University of Miami.
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Journal ArticleDOI
Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines
Asok Mukhopadhyay,Carlos E. Bueso-Ramos,Devasis Chatterjee,Panayotis Pantazis,Bharat B. Aggarwal +4 more
TL;DR: The results suggest that NF-κB and AP-1 may play a role in the survival of prostate cancer cells, and curcumin abrogates their survival mechanisms.
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Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines
TL;DR: It is suggested that curcumin is a potent antiproliferative agent for breast tumor cells and may have potential as an anticancer agent.
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Role of p21 in Apoptosis and Senescence of Human Colon Cancer Cells Treated with Camptothecin
Zhiyong Han,Wenyi Wei,Stephen Dunaway,Stephen Dunaway,James W. Darnowski,Paul Calabresi,John M. Sedivy,Eric A. Hendrickson,Kannan V. Balan,Panayotis Pantazis,James H. Wyche +10 more
TL;DR: It is demonstrated that p21 was required for senescence development of HCT116 cells following treatment with low concentrations of CPT, indicating that apoptosis occurred by a p53- and p21-independent mechanism.
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RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis.
Devasis Chatterjee,Yin Bai,Zhe Wang,Sandy Beach,Stephanie Mott,Rajat Roy,Corey D. Braastad,Yaping Sun,Asok Mukhopadhyay,Bharat B. Aggarwal,James W. Darnowski,Panayotis Pantazis,James H. Wyche,Zheng Fu,Yasuhide Kitagwa,Evan T. Keller,John M. Sedivy,Kam C. Yeung +17 more
TL;DR: The studies suggest that RKIP may represent a novel effector of signal transduction pathways leading to apoptosis and a prognostic marker of the pathogenesis of human cancer cells and tumors after treatment with clinically relevant chemotherapeutic drugs.
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Antiproliferative activity and induction of apoptosis in human colon cancer cells treated in vitro with constituents of a product derived from Pistacia lentiscus L. var. chia
Kannan V. Balan,J. Prince,Zhiyong Han,Konstantinos Dimas,M. Cladaras,James H. Wyche,Nikolaos M. Sitaras,Panayotis Pantazis,Panayotis Pantazis +8 more
TL;DR: The findings presented here suggest that CMG induces an anoikis form of cell death in HCT116 colon cancer cells that includes events associated with caspase-dependent pathways and might be developed into a chemotherapeutic agent for the treatment of human colon and other cancers.