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Showing papers in "Survey of Ophthalmology in 1994"


Journal ArticleDOI
TL;DR: This is the first review that documents the heretofore intuitive claim that early diagnosis is necessary to cure mucormycosis, andHyperbaric oxygen was found to have a favorable effect on prognosis.

403 citations


Journal ArticleDOI
TL;DR: An enhanced understanding of the nature of the optic nerve damage in POAG and improved methods of study may result in earlier diagnosis or allow us to distinguish among different pathological processes all currently grouped under the diagnosis of POAG.

395 citations


Journal ArticleDOI
TL;DR: The regulation of ocular perfusion is different for different parts of the eye and observations on the retina can, therefore, not be extrapolated to the optic nerve head, and a relation between vascular dysregulation and aqueous-humor dynamics is conceivable.

375 citations


Journal ArticleDOI
TL;DR: The treatment success seen with methylprednisolone in the NASCIS 2 study may not generalize to the treatment of traumatic optic neuropathy, and data suggests that treatment must be started within eight hours of injury, making traumatic optic Neuropathy one of the true ophthalmic emergencies.

318 citations


Journal ArticleDOI
TL;DR: Malignant optic glioma is a distinct disease primarily affecting middle-aged adults, and the chiasm is always involved, and although one eye may be spared initially, rapid progression to bilateral blindness is usual.

244 citations


Journal ArticleDOI
TL;DR: Clinicians should remain optimistic about the child's potential for some vision recovery, due to the uncertainty concerning the prognosis in CVI, and the participation of a multidisciplinary team and the use of special visual testing techniques.

225 citations


Journal ArticleDOI
TL;DR: An imbalance of endothelium-derived relaxing and contracting factors could be important for the development of vascular ophthalmic complications like hypertension, diabetes, arteriolosclerosis and retinal ischemia.

197 citations


Journal ArticleDOI
TL;DR: The ophthalmic and systemic manifestations of capillary hemangiomas are discussed in detail, as are the histopathology, radiologic findings, differential diagnosis, and therapeutic alternatives.

164 citations


Journal ArticleDOI
TL;DR: The conclusion is that the pneumatic tonometer provides a high fidelity, noninvasive measure of the intraocular pressure (IOP) pulse and its time variation.

105 citations



Journal ArticleDOI
TL;DR: An extensive review of the prevention, diagnosis, and management of complications associated with blepharoplasty is presented.

Journal ArticleDOI
TL;DR: This review provides historical background, pathophysiology, immuno-genetics, diagnostic testing, and treatment options for ocular myasthenia, as well as a discussion of drug-inducedMyasthenic syndromes.

Journal ArticleDOI
TL;DR: While an increase in the intraocular pressure on assumption of the supine position from the seated or upright position has been known for decades, the recent introduction of a means to quantify the pulsatile ocular blood flow has led to studies indicating a postural decrease in the pulses.

Journal ArticleDOI
TL;DR: In this article, a new method of classifying glaucoma based upon the appearance of the optic nerve is proposed, which is not intended to be all inclusive, but rather to provide a means by which various subtypes of glauca can be better differentiated.

Journal ArticleDOI
TL;DR: A better understanding of the microvasculature of the anterior optic nerve is needed to evaluate its relationship to glaucomatous damage and modulation of this vascular supply, with agents that mimic autoregulatory controls, may allow the sites of vasomotor control to be established and, in the future, their status to be manipulated.

Journal ArticleDOI
TL;DR: The vascular relaxing properties of three beta adrenoceptor antagonists were characterized, compared and contrasted in the porcine long posterior ciliary artery to suggest that this property is much more likely to contribute to any potentially beneficial effects of betaxolol than carteolol or timolol.

Journal ArticleDOI
TL;DR: In this paper, the eosinophil's morphologic, immunologic, and biochemical characteristics are reviewed and its role in certain ophthalmic diseases thoroughly examined, including parasitic infections and allergic and non-allergic diseases.

Journal ArticleDOI
TL;DR: The knowledge of the inter- and intraindividual variation of retinal blood flow indices allows for a priori power estimations for pathophysiologic and pharmacological studies.

Journal ArticleDOI
TL;DR: The complication of anterior segment ischemia as a result of strabismus surgery is reviewed and its potential for producing permanent visual loss is reviewed.

Journal ArticleDOI
TL;DR: Two unusual young patients with intraocular lymphoma who presented clinically with “retinal vasculitis” showed an angiocentric pattern of lymphocytic infiltration and responded favorably to aggressive chemotherapy with long-term survival.

Journal ArticleDOI
TL;DR: Observations indicate that circulatory defects in the optic disk and retina occur in ocular hypertension and open-angle glaucoma and increase with the progression of the disease.

Journal ArticleDOI
TL;DR: Combining B-scan ultrasonography and Doppler waveform analysis, CDI enables noninvasive serial examination of blood velocity and vascular resistance from the ophthalmic, short posterior, ciliary and central retinal arteries.

Journal ArticleDOI
TL;DR: In this article, a prospective, randomized, double-masked study, 44 patients with primary open-angle glaucoma were treated either with 0.5% betaxolol or timolol in both eyes twice daily.

Journal Article
TL;DR: In a prospective, randomized, double-masked study, 44 patients with primary open-angle glaucoma were treated with betaxolol or 0.5% timolol in both eyes twice daily, and both drugs lowered in the intraocular pressure.

Journal ArticleDOI
TL;DR: In this paper, the ocular carbon dioxide reactivity was determined by recording ocular pulse amplitudes (OPA) by means of oculo-oscillo-dynamography (OODG).

Journal Article
TL;DR: An increased carbon dioxide reactivity in some normal pressure glaucoma patients, i.e., a significant increase of OPA and a significant improvement of the central visual field during exposure to increased inspiratory carbon dioxide concentrations, may be due to an initial ocular vasospasm in these patients, which can be released by induced vasodilation due to carbon dioxide exposure.

Journal ArticleDOI
TL;DR: It is concluded that, under isocapnic conditions, retinal perfusion may be regulated to provide constant O2 delivery and retinal capillaries may be recruited as PO2 falls.

Journal ArticleDOI
TL;DR: In both treatment groups, the visual field mean index decreased slightly during the first six months of treatment, but remained so only in the timolol-treated group at all subsequent examinations, suggesting that factors other than IOP alone may determine visual field outcome.

Journal ArticleDOI
TL;DR: The substantial decrease of POBF with increased IOP inLTG eyes compared with normals shows an altered response of the vascular system in LTG, probably consistent with a lack of the myogenic autoregulation in reply to IOP-induced modifications of the perfusion pressure.

Journal Article
TL;DR: In this article, the effect of long-term glaucoma therapy on ocular hemodynamics has taken on increased interest, and the authors measured the pulsatile ocular blood flow (POBF), as derived by the Langham OBF system, prior to treatment and then tracked throughout a one-year period of beta-blocker therapy.