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Showing papers in "The Journal of Thoracic and Cardiovascular Surgery in 1978"


Journal ArticleDOI
TL;DR: There was a significant difference for patients who had metastases to the subcrainal lymph nodes as compared to the prognosis for those who did not, and no significant difference in survival was detected between patients who were given adjuvant therapy and those who were not.

752 citations


Journal ArticleDOI
TL;DR: Blunt esophagectomy without thoracotomy is safe and is far better tolerated physiologically than the combined transthoracic and abdominal operations more traditionally used for exophageal resection and reconstruction.

423 citations


Journal ArticleDOI
TL;DR: A review of tumors from 60 patients with localized pleural mesothelioma seems to justify separation into benign and malignant variants, and no single clinical feature allowed preoperative predictability concerning benignity or malignancy.

328 citations


Journal ArticleDOI
TL;DR: It is concluded that blood cardioplegia, both experimentally and clinically, offers better myocardial protection and operating conditions than does intermittent ischemia or continuous coronary perfusion.

284 citations


Journal ArticleDOI
TL;DR: Using a rat heart model of cardiopulmonary bypass and ischemic cardiac arrest, magnesium is found to be a highly effective component of protective infusates which can be additive to hypothermia and other protective agents.

245 citations


Journal ArticleDOI
TL;DR: The methods currently used at the National Heart Institute in the operative treatment of patients with hypertrophic subaortic stenosis (IHSS) and the criteria of an adequate myotomy are described.

224 citations


Journal ArticleDOI
TL;DR: Card-ac function early postoperatively was good in both groups clinically and according to measurements, but only in the cold cardioplegic group (A) was cardiac index not adversely affected by longer cross-clamp time.

212 citations


Journal ArticleDOI
TL;DR: If carbon dioxide is removed by an extracorporeal membrane lung ventilated with room air, the natural lung can be used for oxygen transport alone; this is demonstrated in lambs by maintaining lungs "inflated" with 100 percent oxygen at constant pressure and removing all carbon dioxide through the membrane lung.

180 citations


Journal ArticleDOI
TL;DR: In this study, autotransfusion of shed mediastinal blood was safe and simple, it significantly reduced bank blood requirements and resulted in substantial financial savings for the patients and the hospital.

174 citations


Journal ArticleDOI
TL;DR: Preoperative and postoperative cardiac catheterization data were analyzed from 10 patients with aortic stenosis and eight withaortic incompetence with normal prosthetic function, finding that left ventricular mass decreased during surgery.

163 citations


Journal ArticleDOI
TL;DR: Assessment of the efficacy of three infusates in a rat heart model of cardiopulmonary bypass and ischemic cardiac arrest indicates that the St. Thomas' Hospital solution is an effective protective agent under all conditions studied but the Bretschneider solution is effective only under hypothermic conditions and the Kirsch solution is ineffective and may exacerbate tissue injury.

Journal ArticleDOI
TL;DR: It is concluded that augmentation of diastolic pressure with alpha adrenergic drugs during CPR improves coronary perfusion and that inotropic drugs may worsen myocardial ischemia during CPR by raising oxygen demands while simultaneously impeding subendocardial blood supply.

Journal ArticleDOI
TL;DR: This study reviewed 2,184 patients who underwent prosthetic valve replacement from 1963 to 1977, with a total follow-up of 7,123 patient-years, and found that glutaraldehyde-preserved heterografts might be more resistant to infection or to certain of its complications than mechanical prosthetic valves.

Journal ArticleDOI
TL;DR: The approach to all pathways is now safe enough to allow the surgeon to offer this operation to patients with life-threatening tachyarrhythmias as well as the ones with rhythm disturbances that are either burdensome or impossible to treat medically.

Journal ArticleDOI
TL;DR: Vulnerability of the preserved tissue to compressive flexure could well affect the long-term durability of the glutaraldehyde-preserved heterograft valve, and this possibility is discussed in relation to the clinical use of these valves.

Journal ArticleDOI
TL;DR: It is concluded that routine placement of atrial wire electrodes at the time of operation is indicated regardless of the nature of the open-heart procedure or the preoperative rhythm.

Journal ArticleDOI
TL;DR: The incidence of perioperative myocardial infarction was examined in 148 patients with known coronary artery disease (CAD) who underwent 226 noncardiac surgical procedures and in 49 patients who had not undergone prior CABG, there were no MI's.

Journal ArticleDOI
TL;DR: During 1972 to 1974, 686 men aged 27 to 67 years, admitted to thirteen Veterans Administration Hospitals with stable angina, resting or exercise electrocardiographic abnormalities, "graftable" arteries, and abnormal left ventricular function were randomly assigned to surgery or medical treatment.

Journal ArticleDOI
TL;DR: A review was made of the presentation, treatment, and follow-up of 20 patients with adenoid cystic carcinoma and 12 patients with mucoepidermoid carcinoma of the bronchus who were seen at the Mayo Clinic during the 50 year period 1927 through 1977.

Journal ArticleDOI
TL;DR: Using an isolated, working rat heart model of cardiopulmonary bypass and ischemic cardiac arrest, it is shown that under certain conditions these additives can be deterimental to tissue protection.

Journal ArticleDOI
TL;DR: A pulse duplicator system for evaluating the hemodynamic performance of mitral prostheses is described and biological valves (Hancock and Ionescu-Shiley) provide an efficient orifice for fluid flow at the free leaflet margins and have large discharge coefficients were shown to yield equally accurate characterizations of valvular hydrodynamic performance.

Journal ArticleDOI
TL;DR: Cardiac performance after repair was better in those in whom a transannular patch was used rather than a valved external conduit and important pulmonary dysfunction postoperatively occurred more often in patients with large "bronchial" arteries than in those without them.

Journal ArticleDOI
TL;DR: Follow-up over a 7 year period shows no clinical, hemodynamic, or angiographic evidence of recoarctation in any of the survivors of aortoplasty with a subclavian flap.

Journal ArticleDOI
TL;DR: Investigation of the optimal technique for myocardial preservation during 120 minutes of ischemic arrest followed by 30 minutes of reperfusion found it was inadequate after hypothermic arrest alone, cardioplegic arrest alone (at normothermia), and single-dose cardioleongia plus hypothermia.

Journal ArticleDOI
TL;DR: In a series of 77 patients treated for bronchopleural fistula over a 13 year period, 49 of whom had postresection fistulas, only 44 were cured of the fistula and 15 died, with the highest rate of fistula closure with the lowest mortality occurred among the 20 patients who underwent myoplasty, usually combined with a limited thoracoplasty.

Journal ArticleDOI
TL;DR: Interoperative protection of the myocardium with hypothermic cardioplegic coronary perfusion with initial cardiac arrest, according to the method of Kirsch, in the authors' experience is superior to hypothermal ischemia, intermittent reperfusion, and coronary perfusions of the beating or fibrillating heart.

Journal ArticleDOI
TL;DR: Marked alterations in levels of circulating thyroid hormone were found in patients undergoing cardiopulmonary bypass with a rise in thefree thyroxine and a fall in the free triiodothyronine levels, suggesting bypass surgery may have a direct inhibitory action on thyroid-stimulating hormone release at the hypothalamo-pituitary level.

Journal ArticleDOI
TL;DR: Diaphragmatic plication should be considered in infants with paradoxical motion of the hemidiaphragm who remain dependent on mechanical ventilatory support for more than 2 weeks postoperatively, as well as in older children who had a more benign postoperative course.

Journal ArticleDOI
TL;DR: One hundred twenty-nine consecutive patients underwent isolated aortic valve replacement with the Hancock porcine xenograft between July, 1974, and December, 1976, and actuarial survival curves show 92 percent of patients alive and well at 24 months' follow-up.

Journal ArticleDOI
TL;DR: An intraluminal graft made of woven tubular Dacron with cloth-covered grooved rings at both ends is used to repair dissecting aneurysms of the thoracic aorta to ensure stable aortic regurgitation in six consecutive white male patients operated upon with the use of this graft.