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Showing papers in "The Journal of Urology in 1977"


Journal ArticleDOI
TL;DR: Although subfertile male subjects with varicoceles had obviously statistically lower sperm densities than volunteers with varICOceles, the testicular sizes were similar and perhaps varicocele ligations should be performed on all male subjectsWith this lesion at an early age to prevent progressive testicular atrophy and decreased fertility potential.

272 citations


Journal ArticleDOI
TL;DR: Adjuctive neph rectomy is a more appropriate term than palliative nephrectomy when referring to removal of the primary tumor as part of an aggresive combined therapeutic approach to treat disseminated renal cell carcinoma.

263 citations


Journal ArticleDOI
TL;DR: There are probably several reasons why some patients have long-term survival (more than 20 years), including patient motivation (better followup), less vascular problems, less chronic decubitus and a higher percentage of lower motor neuron lesions.

252 citations


Journal ArticleDOI
TL;DR: An in vitro model that measures the capacity of different bacterial species to adhere to human vaginal epithelial cells and shows Escherichia coli is shown to adhere more readily to vaginal cells from women with recurrent urinary infection than to similar cells from control women resistant to urinary infection is described.

228 citations


Journal ArticleDOI
TL;DR: The duration of indwelling catheterization seems to be the major factor in squamous changes in these patients, and squamous metaplasia of the bladder was significantly greater in patients who had been catheterized for more than 10 years.

221 citations


Journal ArticleDOI
TL;DR: This is a summary presentation on certain aspects of an experience with the use of radical cystectomy with or without prior irradiation in the treatment of selected patients with bladder cancer at the Memorial Sloan-Kettering Cancer Center.

216 citations


Journal ArticleDOI
TL;DR: The sympathetic innervation of the human bladder neck and female proximal urethra is different from that in other species, a finding that emphasizes the need for caution when results obtained from experimental animals are applied to the human.

195 citations


Journal ArticleDOI
TL;DR: High stage, large size and poor histological differentiation were associated with a significantly higher probability of pelvic node metastases and the response of the primary tumor to irradiation was significantly higher among patients with small stage B tumors and/or those with negative pelvic lymph nodes.

191 citations


Journal ArticleDOI
TL;DR: A series of 238 hydronephrotic kidneys in 219 children is reported, finding many kidneys of initially doubtful value showed useful improvement after reconstructive operation and no secondary nephrectomies were performed.

176 citations


Journal ArticleDOI
TL;DR: The natural history in these cases has been consistent with that of an acquired disorder and the results of urodynamic testing have supported Hinman's contention that the disease is basically a functional one, caused by a discoordination between detrusor contraction and sphincter relaxation.

171 citations


Journal ArticleDOI
TL;DR: The survival rates compare favorably to the national average survival for patients of all ages with localized or regional adenocarcinoma of the prostate and the position of urologists who believe in radical surgical treatment of prostatic cancer is supported.

Journal ArticleDOI
TL;DR: The present regimen of platinum vinblastine and bleomycin has been highly successful, producing 16 complete and 4 partial remissions, making this regimen a major advance in the management of patients with disseminated testicular cancer.

Journal ArticleDOI
TL;DR: It has been determined that testicular descent is an androgen-mediated event directly under the regulation of pituitary gonadotropin and the active androgenic metabolite involved in this process appears to be dihydrotestosterone, which is synthesized by the testis and must be present in high local concentrations to be effective.

Journal ArticleDOI
TL;DR: Determinations of human chorionic gonadotropin and alpha-fetoprotein before lymphadenectomy decreased the error in clinical error in patients with germ cell tumors of the testis.

Journal ArticleDOI
TL;DR: Although the survival rate is severely jeopardized by stromal prostatic invasion the prognosis is not hopeless, and preoperative radiotherapy followed by cystoprostatourethrectomy can be expected to produce a 20 per cent 5-year survival rate.

Journal ArticleDOI
TL;DR: Nephrectomy with hormonal and non-hormonal chemotherapy does improve median survival and 3-year survival significantly and the use of xenogeneic specific immune ribonucleic acid and Bacillus Calmette-Guerin offers promising immunotherapeutic modalities that may be combined with surgical and chemtherapeutic regimens.

Journal ArticleDOI
TL;DR: 48 acceptable cases of idiopathic regression of metastases from renal cell carcinoma culled from the literature are reviewed and 3 additional cases are presented.

Journal ArticleDOI
TL;DR: A new classification of membranous urethra rupture in cases of fractured pelvis is proposed and a plea is made for the more widespread use of retrograde urethrography in patients with a suspected posterior urethral rupture.

Journal ArticleDOI
TL;DR: Anatomical and functional abnormalities were significantly greater in male patients exposed to diethylstilbestrol compared to male controls whose mothers were all participants in a prospective, randomized double-blind study on the effects of diethymal cysts on pregnancy at the authors' hospital during the early 1950s.

Journal ArticleDOI
TL;DR: Since bladder conditions unassociated with bladder outflow obstruction may be responsible for the poor results it is recommended that urine flow rates be measured before an elective prostatic operation so that patients unlikely to benefit from an operation may be identified.

Journal ArticleDOI
TL;DR: A review of 48 patients treated during a 22-year period shows evolution of a regimen of management that has yielded a high percentage of success and resolution occurred in all patients and approximately 50 per cent regained sexual potency.

Journal ArticleDOI
TL;DR: Needle aspiration should be reserved for those patients in whom the clinical findings, roentgenograms and sonography indicate a benign process (that is to confirm that the mass is benign).

Journal ArticleDOI
TL;DR: Over-all followup studies show resolution of pain, hematuria and infection in the vast majority of patients, and X-ray results have since, in general, improved or stabilized.

Journal ArticleDOI
M.J.V. Smith1
TL;DR: It is demonstrated clearly that there is a placebo effect in the management of renal calculous disease and that the only event that clearly separates the 2 groups is complete cessation of calculous formation.

Journal ArticleDOI
TL;DR: Augmentation cystoplasty appears to offer a successful long-term solution for patients with small contracted bladders of almost any etiology and with refined urodynamic diagnostic techniques the over-all failure rate can be expected to decrease.

Journal ArticleDOI
TL;DR: Based on the clinical experience with more than 200 spinal cord subjects and serial urodynamic observations on some of these individuals from the time of injury, various grades of dyssynergia (1 to 3) were recognized and the duration and completeness of suprasacral cord injury essentially determined the degree of Dyssynergy.

Journal ArticleDOI
TL;DR: It is particularly important that the endeavors to improve the end result of the relatively rare severe urethral injuries should not result in over-management of the comparatively minor injuries, since this could increase the stricture potential of many.

Journal ArticleDOI
TL;DR: An embryogenic progression from diverticula to microscopic and macroscopic cysts to radiologically detectable cysts can be established from morphological anomalies found in kidneys from adults.

Journal ArticleDOI
TL;DR: It was observed that electromyographic activity does not always correlate with urethral resistance but must be interpreted in conjunction with other urodynamic parameters, such as urethrals pressures, urinary flow rates and voiding cystourethrography.

Journal ArticleDOI
TL;DR: Of those patients in whom a conservative, non-operative approach was taken 30 per cent ultimately died of renal failure and/or sepsis.