31P NMR studies of enzyme-bound substrates of rabbit muscle pyruvate kinase. Equilibrium constants, exchange rates, and NMR parameters.
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This article is published in Journal of Biological Chemistry.The article was published on 1979-04-25 and is currently open access. It has received 71 citations till now. The article focuses on the topics: Pyruvate kinase.read more
Citations
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Journal ArticleDOI
Mechanism of ATP hydrolysis by beef heart mitochondrial ATPase. Rate constants for elementary steps in catalysis at a single site.
Journal ArticleDOI
Mathematical analysis of enzymic reaction systems using optimization principles.
TL;DR: The analysis of complex dynamic phenomena such as transitions between multiple stationary states, oscillations and even chaotic behaviour in metabolic networks is studied.
Book ChapterDOI
Enzyme–Enzyme Interactions and the Regulation of Metabolic Reaction Pathways
D.K. Srivastava,S.A. Bernhard +1 more
TL;DR: This chapter focuses on enzyme-enzyme interactions and the regulation of metabolic reaction pathways, particularly among soluble mitochondrial enzymes in in vitro experiments.
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Recent developments on structural and functional aspects of the F1 sector of H+-linked ATPases.
Pierre V. Vignais,Michel Satre +1 more
TL;DR: The notion that the proton motive force generated by respiration is required for conformational changes of the F1 sector of the H+-ATPase complex has gained acceptance and is supported by kinetic data and by the demonstration of partial site reactivity in inactivation experiments performed with selective chemical modifiers.
References
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Journal ArticleDOI
Fluorokinase and pyruvic kinase.
Alisa Tietz,Severo Ochoa +1 more
TL;DR: Observations suggest that both the pyruvic kinase and “fluorokinase” reactions are catalyzed by one and the same protein.
Journal ArticleDOI
Kinetic and magnetic resonance studies of the pyruvate kinase reaction. i. divalent metal complexes of pyruvate kinase.
Albert S. Mildvan,Mildred Cohn +1 more
Journal ArticleDOI
Magnetic Resonance Studies of Manganese (II) Binding Sites of Pyruvate Kinase TEMPERATURE EFFECTS AND FREQUENCY DEPENDENCE OF PROTON RELAXATION RATES OF WATER
Jacques Reuben,Mildred Cohn +1 more
TL;DR: It may be concluded that the enzyme probably provides three ligands for Mn(II) and thus the conformational changes previously detected by protein difference spectroscopy due to the binding of a divalent metal ion may be rationalized.
Journal ArticleDOI
Affinity labeling of rabbit muscle pyruvate kinase by 5'-p-fluorosulfonylbenzoyladenosine.
James L. Wyatt,Roberta F. Colman +1 more
TL;DR: The reaction of 5'-p-fluorosulfonylbenzoyladenosine with pyruvate kinase exhibits several of the characteristics of affinity labeling of the enzyme, consistent with the postulate that lysyl or tyrosyl residues are the most probably candidates for the critical amino acids.
Journal ArticleDOI
Equilibrium and Kinetic Studies of the Pyruvic Kinase Reaction
John T. McQuate,Merton F. Utter +1 more
TL;DR: Further studies on the pyruvic kinase reaction are presented including values for the equilibrium constant as a function of pH, the Michaelis constants for the reaction components, and maximal initial velocities for the forward and back reactions.
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