Journal ArticleDOI
31P spin-lattice relaxation times and resonance linewidths of rat tissue in vivo: dependence upon the static magnetic field strength.
Jeffrey L. Evelhoch,Coleen S. Ewy,Barry A. Siegfried,Barry A. Siegfried,Joseph J. H. Ackerman,David W. Rice,Richard W. Briggs +6 more
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TLDR
The spin‐lattice relaxation times of muscle and brain phosphorus metabolites decrease linearly with increasing field strength while those of liver are constant over the range of static fields examined.Abstract:
Phosphorus-31 NMR spin-lattice relaxation times and resonance linewidths of rat leg muscle, brain, and liver metabolites in vivo have been examined at 1.9-, 4.7-, and 8.5-T static magnetic field strengths. The resonance linewidths expressed in ppm that have been measured are independent of field strength. The spin-lattice relaxation times of muscle and brain phosphorus metabolites decrease linearly with increasing field strength while those of liver are constant over the range of static fields examined.read more
Citations
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Journal ArticleDOI
Noninvasive quantitation of phosphorus metabolites in human tissue by NMR spectroscopy
Klaus Roth,B. Hubesch,Dieter J. Meyerhoff,S. Naruse,J. R. Gober,T. J. Lawry,Michael D. Boska,Gerald B. Matson,M. W. Weiner +8 more
TL;DR: In this article, an external reference of hexamethyl phosphoroustriamide was used to quantify metabolite concentrations using 31 P NMR spectroscopy, and the method was applied to seven normal human subjects.
Journal ArticleDOI
Phosphate metabolite imaging and concentration measurements in human heart by nuclear magnetic resonance
TL;DR: Cardiac‐gated phosphorus (31P) nuclear magnetic resonance (NMR) spectroscopic imaging with surface coils resolves in three dimensions the spatial distribution of high energy phosphate metabolites in the human heart noninvasively.
Journal ArticleDOI
Assessment of 31P relaxation times in the human calf muscle: A comparison between 3 T and 7 T in vivo†
Wolfgang Bogner,Marek Chmelik,Albrecht Ingo Schmid,Ewald Moser,Siegfried Trattnig,Stephan Gruber +5 more
TL;DR: At 7 T 31P‐MRS in the human calf muscle offers more than twice as much SNR per unit time in reduced measurement time compared to 3 T, allowing shorter measurements at higher field strengths or up to 62% additional signal‐to‐noise ratio (SNR)per unit time.
Journal ArticleDOI
Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver.
TL;DR: Results indicate that TmDOTP5- promises to be quite useful as an in vivo shift reagent for liver and other organs.
Journal ArticleDOI
Determination of creatine kinase kinetic parameters in rat brain by NMR magnetization transfer. Correlation with brain function.
André Sauter,Markus Rudin +1 more
TL;DR: In the rat brain, like in the heart, the CK forward rate constant kf, in contrast to ATP and PCr levels, is a sensitive reliable indicator of both increased and reduced function.
References
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Journal ArticleDOI
Application of Fourier Transform Spectroscopy to Magnetic Resonance
Richard R. Ernst,W. A. Anderson +1 more
TL;DR: In this paper, the application of a new Fourier transform technique to magnetic resonance spectroscopy is explored, which consists of applying a sequence of short rf pulses to the sample to be investigated and Fourier-transforming the response of the system.
Journal ArticleDOI
Mapping of metabolites in whole animals by 31P NMR using surface coils.
TL;DR: The metabolic state of skeletal muscle and brain within intact rats is monitored using high resolution phosphorus nuclear magnetic resonance, indicating the diagnostic possibilities of the method.
Journal ArticleDOI
The sensitivity of the zeugmatographic experiment involving human samples
D.I Hoult,Paul C. Lauterbur +1 more
TL;DR: In this paper, an attempt is made to remove some of the uncertainty surrounding the sensitivity of an NMR experiment involving human samples, and it is shown that noise may be associated not only with the receiving coil resistance, but also with dielectric and inductive losses in the sample.
Journal ArticleDOI
RF magnetic field penetration, phase shift and power dissipation in biological tissue: Implications for NMR imaging
Paul A. Bottomley,E. R. Andrew +1 more
TL;DR: The results indicate that at NMR operating frequencies much greater than about 30 MHz, magnetic field amplitude and phase variations experienced by the nuclei may cause serious distortions in an image of a human torso.