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Journal ArticleDOI

A Mathematical Model and Sensitivity Assessment of COVID-19 Outbreak for Ghana and Egypt

TLDR
A Susceptible, Exposed, Asymptomatic, Quarantined asymPTomatic, Severely infected, Hospitalized, Recovered, Deceased, and Partially quarantined susceptible individuals is proposed.
Abstract
Following the outbreak of COVID-19 in December 2019, and the eventual spread to other parts of the world; has pushed governments and health authorities to take drastic socioeconomic, sociocultural and sociopolitical measures to curb the spread of the virus, SARS-CoV-2. In this paper, we propose a Susceptible, Exposed, Asymptomatic, Quarantined asymptomatic, Severely infected, Hospitalized, Recovered, Deceased, and Partially quarantined susceptible individuals; thus $(S E A Q I_s H RR^{A} D S_p )$ model to describe the dynamics of COVID-19. We fit the model to real data from Ghana and Egypt to estimate model parameters. We calculate the control and basic reproduction numbers for Egypt and Ghana. Projections for the disease control in Ghana and Egypt are presented. The sensitivity analysis suggests that: a continuous increase in the rate of diagnoses, the rate of quarantine through doubling enhanced contact tracing, and stringent safety measures in hospitals (and/or isolation centres); with a constant supply of effective personal protective equipment's (PPEs) will help reduce the control reproduction number $\mathcal{R}_{c}$, to less than unity as the lockdown measures are been lifted. Adding natural recovery to the model shows that an increase in natural recovery from the asymptomatic stage reduces the control reproduction number. We also noticed that the choice of a force of infection influences the control reproduction number.

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Citations
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Journal ArticleDOI

Global stability and cost-effectiveness analysis of COVID-19 considering the impact of the environment: using data from Ghana

TL;DR: The proposed model fits to real data from Ghana in the time window 12th March 2020 to 7th May 2020, with the aid of python programming language using the least-squares method and formulated based on the sensitivity analysis.
Journal ArticleDOI

Sensitivity assessment and optimal economic evaluation of a new COVID-19 compartmental epidemic model with control interventions.

TL;DR: In this article, the authors proposed a Sensitive, Exposed, Asymptomatic, Quarantined asymptotic, Severely infected, Hospitalized, Recovered, Recovering, Deceased, and Protective susceptible (individuals who observe health protocols) compartmental structure to describe the dynamics of COVID-19.
Journal ArticleDOI

Mathematical Analysis of the Effects of Controls on Transmission Dynamics of SARS-CoV-2

TL;DR: In this article, a deterministic model was developed to study the transmission dynamics of the SARS-CoV-2 with two categories of the susceptible (i.e., Immigrant Susceptibles and Local Susceptible) and the model was shown to have a globally stable disease-free equilibrium point whenever the basic reproduction number R 0 is less than unity.
Journal ArticleDOI

Modeling, Control, and Prediction of the Spread of COVID-19 Using Compartmental, Logistic, and Gauss Models: A Case Study in Iraq and Egypt

TL;DR: In this paper, the authors investigated the spread of the coronavirus disease 2019 (COVID-19) in Iraq and Egypt by using compartmental, logistic regression, and Gaussian models.
Posted ContentDOI

Epidemic Analysis of COVID-19 in Egypt, Qatar and Saudi Arabia using the Generalized SEIR Model

TL;DR: A modified variant of SEIR is implemented to predict the behavior of COVID-19 in Egypt and other countries in the Middle East via Nelder-Mead algorithm to estimate the future dynamics of the pandemic.
References
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Journal ArticleDOI

Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission

TL;DR: A precise definition of the basic reproduction number, R0, is presented for a general compartmental disease transmission model based on a system of ordinary differential equations and it is shown that, if R0<1, then the disease free equilibrium is locally asymptotically stable; whereas if R 0>1,Then it is unstable.
Journal ArticleDOI

A conceptual model for the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China with individual reaction and governmental action.

TL;DR: A conceptual models for the COVID-19 outbreak in Wuhan with the consideration of individual behavioural reaction and governmental actions is proposed, and it successfully captures the course of the COIDs, and thus sheds light on understanding the trends of the outbreak.
Book

An Introduction to Mathematical Epidemiology

TL;DR: The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of infectious diseases and includes various techniques for the computation of the basic reproduction number as well as approaches to the epidemiological interpretation of the reproduction number.
Journal ArticleDOI

Responding to global infectious disease outbreaks: lessons from SARS on the role of risk perception, communication and management.

TL;DR: The role that risk, and especially the perception of risk, its communication and management, played in driving the economic impact of SARS is examined and the potential for the rapid spread of infectious disease is not necessarily a greater threat than it has always been, but the effect that an outbreak can have on the economy is, which requires further research and policy development.
Posted ContentDOI

Epidemic analysis of COVID-19 in China by dynamical modeling

TL;DR: A mathematical model is proposed to analyzes this epidemic, based on a dynamic mechanism that incorporating the intrinsic impact of hidden la- tent and infectious cases on the entire process of transmission, which indicates that, the outbreak in Wuhan is predicted to be ended in the early April.
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