A new approach for the synthesis of bisindoles through AgOTf as catalyst
TLDR
The simplicity and easy operational methodology using a small amount of commercially available AgOTf, one of the lowest catalytic charge used in this process to date, makes this procedure an alternative approach for this interesting and appealing reaction.Abstract:
A novel approach for the catalyzed formation of bisindolylmethane derivatives (BIMs) is described. This methodology is the unique example where AgOTf has been successfully used for the activation of aldehydes, giving easy access to a broad range of bisindolyl derivatives with excellent results. Moreover, the simplicity and easy operational methodology using a small amount of commercially available AgOTf (1–3 mol %), one of the lowest catalytic charge used in this process to date, makes this procedure an alternative approach for this interesting and appealing reaction.read more
Citations
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Transition Metal-Catalyzed CH Activation of Indoles
TL;DR: Recent advances and strategies for transition metal-catalyzed CH activation of indoles and a versatile tool box for the preparation of structurally diverse indoles are discussed.
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Expedient Access to Unsymmetrical Diarylindolylmethanes through Palladium-Catalyzed Domino Electrophilic Cyclization-Extended Conjugate Addition Approach.
TL;DR: A palladium-catalyzed domino process to access unsymmetrical diarylindolylmethanes has been developed through the annulation of o-alkynylanilines followed by 1,6-conjugate addition with p-quinone methides (p-QMs) under relatively mild conditions.
Journal ArticleDOI
Synthesis of bis(indolyl)methanes using ammonium niobium oxalate (ANO) as an efficient and recyclable catalyst
Samuel R. Mendes,Samuel Thurow,Filipe Penteado,Maite S. da Silva,Rogério A. Gariani,Gelson Perin,Eder J. Lenardão +6 more
TL;DR: A green and efficient procedure was developed for the synthesis of bis(indolyl)methanes using ammonium niobium oxalate (ANO) NH4[NbO(C2O4)2(H2O)x]·nH 2O as the catalyst and water or glycerol as the solvent.
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Tetranuclear Zn/4f coordination clusters as highly efficient catalysts for Friedel–Crafts alkylation
Kieran Griffiths,Prashant Kumar,Geoffrey R. Akien,Nicholas F. Chilton,Alaa Abdul-Sada,Graham J. Tizzard,Simon J. Coles,George E. Kostakis +7 more
TL;DR: A series of custom-designed, high yield, isoskeletal tetranuclear Zn/4f coordination clusters showing high efficiency as catalysts with low catalytic loadings in Friedel-Crafts alkylation are described for the first time.
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The natural and synthetic indole weaponry against bacteria
Maria Gessica Ciulla,Kamal Kumar +1 more
TL;DR: A brief account of indole based antibacterial small molecules which have been either synthesized in the laboratory or isolated from natural sources and provide intriguing potential leads in the antibiotic drug discovery research are presented.
References
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