Journal ArticleDOI
A randomized-controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis-induced hypotension [ALPS trial].
Rakhi Maiwall,Abhinav Kumar,Samba Siva Rao Pasupuleti,A. Hidam,Harsh Vardhan Tevethia,Guresh Kumar,Amrish Sahney,Lalita Gouri Mitra,Shiv Kumar Sarin +8 more
TLDR
In this paper , the authors compared the efficacy and safety of 20% albumin to plasmalyte in reversing sepsis-induced hypotension in critically ill patients with cirrhosis.About:
This article is published in Journal of Hepatology.The article was published on 2022-04-01. It has received 19 citations till now. The article focuses on the topics: Medicine & Medicine.read more
Citations
More filters
Journal ArticleDOI
Hepatic perfusion as a new predictor of prognosis and mortality in critical care patients with acute-on-chronic liver failure
Johannes Vogg,Constantin Maier-Stocker,Stefan Munker,Alexander Mehrl,S Schlosser,H. Tews,Karsten Gülow,Martina Müller,S Schmid +8 more
TL;DR: The prognostic value of the assessment of hepatic perfusion in critical care patients with severe liver diseases by bedside Doppler ultrasound examination is shown and its utility as an accurate predictor of the outcome in patients with ACLF is shown.
Journal ArticleDOI
Development of a nomogram for predicting 90-day mortality in patients with sepsis-associated liver injury
TL;DR: In this paper , the authors developed an accurate forecasting nomogram to estimate individual 90-day mortality in SALI patients, which can be used to assess the prognosis of patients with SALI and may assist in guiding clinical practice to enhance patient outcomes.
Journal ArticleDOI
A randomized-controlled trial (TARGET-C) of high vs. low target mean arterial pressure in patients with cirrhosis and septic shock.
Rakhi Maiwall,Samba Siva Rao Pasupuleti,A. Hidam,Anupam Kumar,Harsh Vardhan Tevethia,Rajan Vijayaraghavan,Sherin Sarah Thomas,R. P. Mathur,Guresh Kumar,Shiv Kumar Sarin +9 more
TL;DR: In this paper , the efficacy of a high (80-85 mmHg; H-MAP) vs. low (60-65, L-MAP), target MAP strategy in improving 28-day mortality in CICs was compared.
Journal ArticleDOI
Cirrhosis Management in the Intensive Care Unit
TL;DR: In this paper , the authors discuss appropriate considerations and evidence-based practices for the general care of patients with cirrhosis and critical illness in the critical care unit of acute-on-chronic liver failure.
References
More filters
Journal ArticleDOI
A comparison of albumin and saline for fluid resuscitation in the intensive care unit
TL;DR: In patients in the ICU, use of either 4 percent albumin or normal saline for fluid resuscitation results in similar outcomes at 28 days, with no significant differences between the groups.
Journal ArticleDOI
EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
Paolo Angeli,Mauro Bernardi,Càndid Villanueva,Claire Francoz,Rajeshwar P. Mookerjee,Jonel Trebicka,Aleksander Krag,Wim Laleman,Pere Ginès +8 more
TL;DR: The panel of experts, having emphasised the importance of initiating aetiologic treatment for any degree of hepatic disease at the earliest possible stage, extended its work to all the complications of cirrhosis which had not been covered by the European Association for the Study of the Liver guidelines.
Journal ArticleDOI
Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Manu Shankar-Hari,Manu Shankar-Hari,Gary Phillips,Mitchell L. Levy,Christopher W. Seymour,Vincent X. Liu,Clifford S. Deutschman,Clifford S. Deutschman,Derek C. Angus,Gordon D. Rubenfeld,Gordon D. Rubenfeld,Mervyn Singer +11 more
TL;DR: A consensus process using results from a systematic review, surveys, and cohort studies found that adult patients with septic shock can be identified using the clinical criteria of hypotension requiring vasopressor therapy to maintain mean BP 65 mm Hg or greater and having a serum lactate level greater than 2 mmol/L after adequate fluid resuscitation.
Journal ArticleDOI
EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis.
TL;DR: There is a clear rationale for the management of ascites in patients with cirrhosis, as successful treatment may improve outcome and symptoms, and patients with ascites should generally be considered for referral for liver transplantation.
Journal ArticleDOI
Albumin Replacement in Patients with Severe Sepsis or Septic Shock
Pietro Caironi,Gianni Tognoni,Serge Masson,Roberto Fumagalli,Antonio Pesenti,Marilena Romero,Caterina Fanizza,Luisa Caspani,Stefano Faenza,Giacomo Grasselli,Gaetano Iapichino,Massimo Antonelli,Vieri Parrini,Gilberto Fiore,Roberto Latini,Luciano Gattinoni,Abstr Act +16 more
TL;DR: In patients with severe sepsis, albumin replacement in addition to crystalloids, as compared with crystalloids alone, did not improve the rate of survival at 28 and 90 days.