Journal ArticleDOI
EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis.
TLDR
There is a clear rationale for the management of ascites in patients with cirrhosis, as successful treatment may improve outcome and symptoms, and patients with ascites should generally be considered for referral for liver transplantation.About:
This article is published in Journal of Hepatology.The article was published on 2010-08-30. It has received 1476 citations till now. The article focuses on the topics: Spontaneous bacterial peritonitis & Hepatorenal syndrome.read more
Citations
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Journal ArticleDOI
EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
Paolo Angeli,Mauro Bernardi,Càndid Villanueva,Claire Francoz,Rajeshwar P. Mookerjee,Jonel Trebicka,Aleksander Krag,Wim Laleman,Pere Ginès +8 more
TL;DR: The panel of experts, having emphasised the importance of initiating aetiologic treatment for any degree of hepatic disease at the earliest possible stage, extended its work to all the complications of cirrhosis which had not been covered by the European Association for the Study of the Liver guidelines.
Journal ArticleDOI
Renal Failure in Cirrhosis
Pere Ginès,Robert W. Schrier +1 more
TL;DR: This review discusses recently identified information about renal failure in cirrhosis and clinical interventions that may assist in the prevention and management of this complication.
Journal ArticleDOI
Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013
Rajiv Jalan,Javier Fernández,Reiner Wiest,Bernd Schnabl,Richard Moreau,Paolo Angeli,Vanessa Stadlbauer,Thierry Gustot,Mauro Bernardi,Rafael Cantón,Agustín Albillos,Frank Lammert,Alexander Wilmer,Rajeshwar P. Mookerjee,Jordi Vila,R. Garcia-Martinez,Julia Wendon,José Such,Juan Córdoba,Arun J. Sanyal,Guadalupe Garcia-Tsao,Vicente Arroyo,Andrew K. Burroughs,Pere Ginès +23 more
TL;DR: An in-depth review and a position statement on bacterial infections in cirrhosis are reported, which suggest that research on biomarkers of early infection may be useful in early diagnosis and treatment of infections.
Journal ArticleDOI
Introduction to the revised American Association for the Study of Liver Diseases Practice Guideline management of adult patients with ascites due to cirrhosis 2012
TL;DR: This version of the American Association for the Study of Liver Diseases Practice Guideline is the fourth iteration of this guideline and represents a thorough update of the 2009 version.
Journal ArticleDOI
EASL Clinical Practice Guidelines on nutrition in chronic liver disease
Manuela Merli,Annalisa Berzigotti,Shira Zelber-Sagi,Srinivasan Dasarathy,Sara Montagnese,Laurence Genton,Mathias Plauth,Albert Parés +7 more
TL;DR: These Clinical Practice Guidelines review the present knowledge in the field of nutrition in chronic liver disease and promote further research on this topic, with recommendations provided in specific settings such as hepatic encephalopathy, cirrhotic patients with bone disease, patients undergoing liver surgery or transplantation and critically ill cirrhosis patients.
References
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Journal ArticleDOI
Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group.
TL;DR: A 2-day consensus conference on acute renal failure (ARF) in critically ill patients was organized by ADQI as discussed by the authors, where the authors sought to review the available evidence, make recommendations and delineate key questions for future studies.
Journal ArticleDOI
A model to predict survival in patients with end‐stage liver disease
Patrick S. Kamath,Russell H. Wiesner,Michael Malinchoc,Walter K. Kremers,Terry M. Therneau,Catherine L. Kosberg,Gennaro D'Amico,E. Rolland Dickson,M.B.A. W. Ray Kim M.D. +8 more
TL;DR: The MELD scale is a reliable measure of mortality risk in patients with end‐stage liver disease and suitable for use as a disease severity index to determine organ allocation priorities in patient groups with a broader range of disease severity and etiology.
Journal ArticleDOI
Intensive insulin therapy and pentastarch resuscitation in severe sepsis.
Frank M. Brunkhorst,Christoph Engel,Frank Bloos,Andreas Meier-Hellmann,Max Ragaller,Norbert Weiler,Onnen Moerer,Matthias Gruendling,Michael Oppert,Stefan Grond,Derk Olthoff,Ulrich Jaschinski,Stefan John,Rolf Rossaint,Tobias Welte,Martin Schaefer,Peter M. Kern,Evelyn Kuhnt,Michael Kiehntopf,Christiane S. Hartog,Charles Natanson,Markus Loeffler,Konrad Reinhart +22 more
TL;DR: The use of intensive insulin therapy placed critically ill patients with sepsis at increased risk for serious adverse events related to hypoglycemia and HES was harmful, and its toxicity increased with accumulating doses.
Journal ArticleDOI
Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis
Vicente Arroyo,Pere Ginès,Alexander L. Gerbes,F J Dudley,Paolo Gentilini,Giacomo Laffi,Telfer B. Reynolds,H. Ring-Larsen,J Schölmerich +8 more
Journal ArticleDOI
Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis.
TL;DR: The stimulation of the renin‐angiotensin‐aldosterone system, vasopressin release and sympathetic nervous system associated with cirrhosis is not consonant with primary volume expansion, and favors the “overflow” hypothesis.