Journal ArticleDOI
A Re-examination of the Alkaloids of Lupinus cosentinii
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This article is published in Journal of Natural Products.The article was published on 1979-07-01. It has received 23 citations till now.read more
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Journal ArticleDOI
Indolizidine and quinolizidine alkaloids
TL;DR: This review covers the isolation, structure determination, synthesis, chemical transformations and biological activity of indolizidine and quinolIZidine alkaloids.
Journal ArticleDOI
Bioactive cyclobutane-containing alkaloids
TL;DR: Research on novel natural cyclobutane-containing alkaloids and synthetic compounds isolated from terrestrial and marine species, confirmed to show antimicrobial, antibacterial, anticancer, and other activities are described.
Journal ArticleDOI
Organocatalytic asymmetric Mannich cyclization of hydroxylactams with acetals: total syntheses of (-)-epilupinine, (-)-tashiromine, and (-)-trachelanthamidine.
TL;DR: An asymmetric, organocatalytic, one-pot Mannich cyclization between a hydroxylactam and acetal is described to provide fused, bicyclic alkaloids bearing a bridgehead N’atom.
Journal ArticleDOI
Total Syntheses of (−) Epilupinine and (−)-Tashiromine Using Imino-Aldol Reactions
Amanda C. Cutter,Iain R. Miller,John F. Keily,Richard K. Bellingham,Mark E. Light,Richard C. D. Brown +5 more
TL;DR: High levels of syn selectivity were obtained using lithium enolates of phenyl esters in combination with tert-butylsulfinyl imines to develop short routes to enantiomerically pure indolizidine and quinolIZidine alkaloids.
Journal ArticleDOI
A biomimetic approach for bicyclic alkaloids using acetal pro-nucleophile: total synthesis of (±)-epilupinine and formal syntheses of (±)-laburnine, (±)-isoretronecanol, (±)-tashiromine
TL;DR: In this article, a direct Mannich type diastereoselective biomimetic cyclization using acetal as a pro-nucleophile leading to the hydroxymethyl substituted bicyclic framework of various bicyclic alkaloids is presented.