Journal ArticleDOI
A simple method for determination of serum catalase activity and revision of reference range
TLDR
The catalase assay performed using polarographic and spectrophotometric determination of hydrogen peroxide yielded a good correlation and in 742 healthy individuals the mean and SD values of serumCatalase were 50.5 +/- 18.1 kU/l with 17.7% higher activity in males than in females.About:
This article is published in Clinica Chimica Acta.The article was published on 1991-02-15. It has received 1780 citations till now. The article focuses on the topics: Catalase & Hydrogen peroxide.read more
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Journal ArticleDOI
Nanoparticle-Enhanced Radiotherapy to Trigger Robust Cancer Immunotherapy.
TL;DR: A unique nanomedicine approach as a next‐generation radiotherapy strategy to enable synergistic whole‐body therapeutic responses after local treatment, greatly promising for clinical translation is presented.
Journal ArticleDOI
Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses
Yu Chao,Ligeng Xu,Chao Liang,Liangzhu Feng,Jun Xu,Ziliang Dong,Longlong Tian,Xuan Yi,Kai Yang,Zhuang Liu +9 more
TL;DR: In this paper, an intratumoral injection of a sodium alginate formulation containing catalase (Cat) labelled with the therapeutic 131I radioisotope enables long-term relief of tumour hypoxia and complete tumour elimination at low radioactivity doses.
Journal ArticleDOI
Catalase-Loaded TaOx Nanoshells as Bio-Nanoreactors Combining High-Z Element and Enzyme Delivery for Enhancing Radiotherapy.
Guosheng Song,Yuyan Chen,Chao Liang,Xuan Yi,Jingjing Liu,Xiaoqi Sun,Sida Shen,Kai Yang,Zhuang Liu +8 more
TL;DR: A novel type of bio-nanoreactor with catalase loaded inside TaOx hollow nanoshells is fabricated via a mild one-step method to synergistically enhance the efficacy of cancer radiotherapy by both depositing radiation energy within the tumor and overcoming hypoxia-induced radiotherapy resistance.
Journal ArticleDOI
Smart Nanoreactors for pH-Responsive Tumor Homing, Mitochondria-Targeting, and Enhanced Photodynamic-Immunotherapy of Cancer.
Guangbao Yang,Ligeng Xu,Jun Xu,Rui Zhang,Guosheng Song,Yu Chao,Liangzhu Feng,Fengxuan Han,Ziliang Dong,Bin Li,Zhuang Liu +10 more
TL;DR: A unique type of enzyme-encapsulated, photosensitizer-loaded hollow silica nanoparticles with rationally designed surface engineering as smart nanoreactors are designed, which show enhanced retention responding to the acidic tumor microenvironment and are able to further target mitochondria, the cellular organelle most sensitive to ROS.
Journal ArticleDOI
The influence of trehalose, taurine, cysteamine and hyaluronan on ram semen Microscopic and oxidative stress parameters after freeze-thawing process.
TL;DR: Catalase (CAT) activities were higher in the group that was applied 25mM taurine as an antioxidant, than in all of the other groups in this study, and the addition of antioxidants did not cause significant differences in levels of malondialdehyde (MDA), glutathione (GSH), and glutATHione peroxidase (G SH-Px), after thawing, when compared to groups with no additives.
References
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Book
Clinical Laboratory methods
TL;DR: Clinical laboratory methods, Clinical laboratory methods , کتابخانه مرکزی دانشگاه علوم پزشدکی اتهران.
Journal ArticleDOI
Estimation of serum total lipids
D.D. Woodman,C.P. Price +1 more
TL;DR: A method is presented which provides a rapid reliable procedure for the estimation of total lipids in serum which compares favourably with those obtained by established gravimetric and turbidimetric techniques.
Journal ArticleDOI
Simultaneous determination of superoxide dismutase and catalase in biological materials by polarography.
A. Rigo,G. Rotilio +1 more
TL;DR: The polarographic method of catalytic currents applied to a wave of oxygen permits the simultaneous assay of superoxide dismutase and catalase in biological materials with high speed and reproducibility and minimal manipulation of tissues.
Journal Article
Serum catalase enzyme activity in liver diseases
TL;DR: Serum catalase activity was moderately increased in fatty liver, acute alcoholic hepatitis and in the decompensated form of cardiac circulatory failure and an inexpensive assay of serum catal enzyme activity is suggested for the detection of severe liver cell damage.