Journal ArticleDOI
A synthon approach to spiro compounds
Reads0
Chats0
TLDR
Synthesis of spiro and hetero spiro compounds has been reviewed on the basis of a synthon approach along with their biological activities and photochromism in this paper, where the synthesis process is described in detail.About:
This article is published in Tetrahedron.The article was published on 2006-01-30. It has received 190 citations till now. The article focuses on the topics: Synthon & Photochromism.read more
Citations
More filters
Journal ArticleDOI
Applications of Multicomponent Reactions to the Synthesis of Diverse Heterocyclic Scaffolds
TL;DR: This work has shown that the optimal MCR is sufficiently flexible that it can be employed to generate adducts bearing a variety of functional groups that may then be selectively paired to enable different cyclization manifolds, thereby leading to a diverse collection of products.
Journal ArticleDOI
Metal complex catalysis in the synthesis of spirocarbocycles.
Journal ArticleDOI
Review of synthesis and various biological activities of spiro heterocyclic compounds comprising oxindole and pyrrolidine moities
TL;DR: A representative synthetic scheme and various biological activities of the heterocycles like spiropyrrolidines and oxindole moieties derivatives, especially in relation to microbial infections like cancer and tubercular, viral, HIV, bacterial, and fungal infections are presented.
Journal ArticleDOI
Glycerol as a biodegradable and reusable promoting medium for the catalyst-free one-pot three component synthesis of 4H-pyrans
TL;DR: Glycerol is applied as a green, biodegradable and reusable promoting medium for one-pot three component synthesis of 4H-pyrans under catalyst-free conditions.
Journal ArticleDOI
Organocatalytic Asymmetric Vinylogous α-Ketol Rearrangement: Enantioselective Construction of Chiral All-Carbon Quaternary Stereocenters in Spirocyclic Diketones via Semipinacol-Type 1,2-Carbon Migration
TL;DR: The catalytic enantioselective synthesis of all-carbon quaternary stereogenic centers in spirocyclic diketones has been achieved for the first time by an unprecedented asymmetric vinylogous alpha-ketol rearrangement in which an enantiocontrolled semipinacol-type 1,2-carbon migration was realized using multifunctional cinchona-modified primary amine catalysis.
References
More filters
Journal ArticleDOI
Spiropyrans and Spirooxazines for Memories and Switches
Book ChapterDOI
Chemotaxonomie der Pflanzen
TL;DR: In this article, drei verschiedene Indices anzufertigen: (1) Taxonomic Index, (2) Subject Index, and (3) Chemotaxonomie-index.
Journal ArticleDOI
Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors
Mark S. Kramer,N.R. Cutler,John P. Feighner,Ram K. Shrivastava,John Carman,John J. Sramek,Scott A. Reines,Guanghan Liu,Duane B. Snavely,Edwina Wyatt-Knowles,Jeffrey J. Hale,Sander G. Mills,Malcolm MacCoss,Christopher John Swain,Timothy Harrison,Raymond G. Hill,Franz Hefti,Edward M. Scolnick,Margaret A. Cascieri,Gary G. Chicchi,Sharon Sadowski,Angela Williams,Louise Hewson,David D. Smith,Emma J. Carlson,Richard Hargreaves,Nadia M.J. Rupniak +26 more
TL;DR: The localization of substance P in brain regions that coordinate stress responses and receive convergent monoaminergic innervation suggested that substance P antagonists might have psychotherapeutic properties was found to be correct.