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A technique for the non-invasive estimation of cerebral blood flow in the newborn infant.

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This article is published in Journal of Medical Engineering & Technology.The article was published on 1977-09-01. It has received 22 citations till now. The article focuses on the topics: Cerebral blood flow.

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Citations
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Journal ArticleDOI

Hypoxic-Ischemic Encephalopathy in the Newborn

Gerald M. Fenichel
- 01 May 1983 - 
TL;DR: The immediate treatment of the asphyxiated term newborn requires attention to the derangements in multiple organ systems and the use of anticonvulsants when indicated.
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Measurement of Cerebral Oxygen Consumption in the Human Neonate Using Near Infrared Spectroscopy: Cerebral Oxygen Consumption Increases with Advancing Gestational Age

TL;DR: It is concluded that CVo2 can be estimated in sick neonates using noninvasive optical methods, and the values obtained are in agreement with values which would be expected from the known rate of cerebral glucose consumption in neonates.
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Clinical events relating to intraventricular haemorrhage in the newborn.

TL;DR: It is suggested that fluctuations of systemic blood pressure from initial low levels may be important in the pathogenesis of IVH and that changes in cerebral blood flow are of even greater significance.
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Plethysmographic validation of near infrared spectroscopic monitoring of cerebral blood volume.

TL;DR: The validation of measurement of cerebral blood volume (CBV) and cerebral blood flow (CBF) using near infrared spectroscopy against jugular venous occlusion plethysmography is described, confirming the possibility of using NIRS to monitor CBV continuously in the premature infant.
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Beagle puppy model of intraventricular hemorrhage Randomized indornethacin prevention trial

TL;DR: Nine percent of all pups receiving indomethacin experienced intraventricular hemorrhage, compared with 80% of animals who received the saline vehicle, and significant alterations in the blood pressure responses to the hemorrhagic hypotension/volume reexpansion insult were noted in this group when compared with control animals.
References
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The nitrous oxide method for the quantitative determination of cerebral blood flow in man: theory, procedure and normal values

TL;DR: The present report constitutes a description of the technique as it has now employed it in over 300 determinations, an examination of its underlying theory and validity, and values obtained with its use in 34 studies on 14 normal young men.
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On the Regulation of the Blood‐supply of the Brain

TL;DR: The ease with which one can obtain results upon certain points on taking up the subject is itself apt to make the inquiirer careless in controlling sources of error, which, it may be noted, are some of them not at first sigrht obvious.
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The measurement of volume changes in human limbs.

TL;DR: Volume plethysmography has proved particularly useful in investigations on vasomotor response and, combined with the venous occlusion procedure, has become the standard method for estimating peripheral blood flow in man.
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Origin of intraventricular haemorrhage in the preterm infant.

TL;DR: It is suggested that the capillaries within the germinal layer may be ruptured by a rise in arterial pressure, particularly in conditions of hypercapnia and hypoxia.
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Regional cerebral blood flow in man determined by krypton85

TL;DR: The same technic has recently been applied to the study of myocardial and renal blood flow in animal experiments utilizing the low incidence gamma-emission of Kr85.