Journal ArticleDOI
Acrylic acid copolymer nanoparticles for drug delivery: I. Characterization of the surface properties relevant for in vivo organ distribution
TLDR
In this paper, copolymer nanoparticles of acrylic acid, acrylamide, acrylic acid butyl ester and methacrylic acid methyl ester with increasing acrylic acid content were produced by emulsion polymerization.About:
This article is published in International Journal of Pharmaceutics.The article was published on 1992-07-15. It has received 39 citations till now. The article focuses on the topics: Acrylic acid & Methacrylic acid.read more
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Surface and Colloid Science
TL;DR: In this paper, Ozaki et al. describe the dynamics of adsorption and Oxidation of organic Molecules on Illuminated Titanium Dioxide Particles Immersed in Water.
Journal ArticleDOI
Polymeric nanoparticles for the drug delivery to the central nervous system.
TL;DR: Polymeric Np have been shown to be promising carriers for CNS drug delivery due to their potential both in encapsulating drugs, hence protecting them from excretion and metabolism, and in delivering active agents across the blood–brain barrier without inflicting any damage to the barrier.
Journal ArticleDOI
Analysis of plasma protein adsorption on polymeric nanoparticles with different surface characteristics.
TL;DR: Polymeric latex particles with strongly differing surface properties were synthesized as models for colloidal drug carriers for tissue-specific drug targeting via the intravenous route and protein-nanoparticle interactions were studied.
Journal ArticleDOI
Nanocarriers for the treatment of glioblastoma multiforme: Current state-of-the-art.
TL;DR: The features of blood-brain barrier, and its anatomical changes with different stages of tumor growth are described, and various strategies to improve brain drug delivery i.e. tight junction opening, chemical modification of the drug, efflux transporter inhibition, convection-enhanced delivery and drug delivery nanosystems are discussed.
Journal ArticleDOI
Preparation and in vitro evaluation of calcium-induced soy protein isolate nanoparticles and their formation mechanism study.
TL;DR: In vitro study indicated that the SPI nanoparticles were non-toxic and mainly located in the cytoplasm when uptaken into Caco-2 cells, and calcium favoured the development of β-sheet structures to form SPI aggregates stabilised by hydrogen bonding.
References
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Journal ArticleDOI
Analysis of Macromolecular Polydispersity in Intensity Correlation Spectroscopy: The Method of Cumulants
TL;DR: The first order electric field correlation function of laser light scattered by polydisperse solutions of macromolecules can be written as a sum or distribution of exponentials, with decay rates proportional to the diffusion coefficients of the solute molecules as discussed by the authors.
Book
Surface and Colloid Science
TL;DR: In this paper, Ozaki et al. describe the dynamics of adsorption and Oxidation of organic Molecules on Illuminated Titanium Dioxide Particles Immersed in Water.
Journal ArticleDOI
Blood clearance and organ deposition of intravenously administered colloidal particles. The effects of particle size, nature and shape
TL;DR: In this paper, the importance of particle size, shape and nature was investigated in the blood clearance and organ deposition of polystyrene and cellulose (DEAE) particles in the rabbit using labelled material and the technique of gamma scintigraphy.