Journal ArticleDOI
Age-related changes in prefrontal cortex activity are associated with behavioural deficits in both temporal and spatial context memory retrieval in older adults
TLDR
The fMRI results suggest that age-related deficits in both spatial and temporal context retrieval may be linked to functional changes in right dorsolateral and left medial anterior PFC (APFC) function, and imply that older adults attempt to compensate for these deficits by engaging left dorsol lateral PFC during spatial context retrieval and right APFC during temporal context retrieved.Citations
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Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268
Journal ArticleDOI
Cognitive function, physical activity, and aging: Possible biological links and implications for multimodal interventions
TL;DR: My review of the most recent relevant publications concerning this topic supports the notion that it is a promising approach to provide cognitive training and PA in conjunction, since the combination may generate synergistic beneficial changes than either one individually.
Journal ArticleDOI
Association between prefrontal activity and volume change in prefrontal and medial temporal lobes in aging and dementia: A review
David Maillet,M. Natasha Rajah +1 more
TL;DR: It is concluded that PFC activity is related to age-related changes in local and distal GM volume reductions and that consideration of these structural measures aids the interpretation of fMRI results.
Journal ArticleDOI
Episodic memory function is associated with multiple measures of white matter integrity in cognitive aging.
Samuel N. Lockhart,Adriane B. V. Mayda,Alexandra E. Roach,Evan Fletcher,Owen Carmichael,Pauline Maillard,Christopher G. Schwarz,Andrew P. Yonelinas,Charan Ranganath,Charles DeCarli +9 more
TL;DR: The results suggest that white matter injury to multiple pathways, including connections of frontal and temporal cortex and frontal-subcortical white matter tracts, plays a critical role in memory differences seen in older individuals.
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From mind wandering to involuntary retrieval: Age-related differences in spontaneous cognitive processes.
David Maillet,Daniel L. Schacter +1 more
TL;DR: These studies suggest that older adults exhibit a reduction in frequency of both mind-wandering and involuntary autobiographical memory, whereas findings regarding intrusive thoughts have been more mixed.
References
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Book
Statistical Power Analysis for the Behavioral Sciences
TL;DR: The concepts of power analysis are discussed in this paper, where Chi-square Tests for Goodness of Fit and Contingency Tables, t-Test for Means, and Sign Test are used.
Journal ArticleDOI
“Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician
Marshal F. Folstein,Marshal F. Folstein,Susan E B Folstein,Susan E B Folstein,Paul R. McHugh,Paul R. McHugh +5 more
TL;DR: A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
A practical method for grading the cognitive state of patients for the clinician
TL;DR: The Mini-Mental State (MMS) as mentioned in this paper is a simplified version of the standard WAIS with eleven questions and requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
Journal ArticleDOI
An inventory for measuring depression
TL;DR: The difficulties inherent in obtaining consistent and adequate diagnoses for the purposes of research and therapy have been pointed out and a wide variety of psychiatric rating scales have been developed.