Journal ArticleDOI
Alcoholism: III. Diagnosis and Familial Psychiatric Illness in 259 Alcoholic Probands
TLDR
Among the first-degree relatives of the alcoholic probands psychopathy was increased when compared to general population figures and brothers and fathers of male alcoholics showed considerably more alcoholism than would be expected.Abstract:
IN HIS clinical and genetic study of male alcoholics Amark presented the risks for psychiatric diseases in the probands' relatives. 1 When compared to general population figures the families of the alcoholic probands showed no increase in schizophrenia, manic depressive disease, general paresis, senile and presenile psychoses, epilepsy, or oligophrenia. Psychogenic psychoses were, however, more frequently found in the relatives of alcoholics than in the general population. Although psychogenic psychoses contain three different categories, depressive syndromes, disturbances of consciousness, and paranoid syndromes, the most common form of illness in this group is psychogenic depression. Psychogenic depressions fit into the general framework of affective disorder. Among the first-degree relatives of the alcoholic probands psychopathy was also increased when compared to general population figures. Finally, brothers and fathers of male alcoholics showed considerably more alcoholism than would be expected although female first-degree relatives (sisters and mothers) did not show a remarkablyread more
Citations
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Inheritance of alcohol abuse. Cross-fostering analysis of adopted men
TL;DR: The inheritance of alcoholism was studied in 862 Swedish men adopted by nonrelatives at an early age and found that both the congenital and postnatal backgrounds of the adoptees modify their risk for alcohol abuse.
Journal ArticleDOI
Alcohol Problems in Adoptees Raised Apart From Alcoholic Biological Parents
TL;DR: It is suggested that genetic factors may play a role in the development of alcohol problems in men separated from their biological parents early in life where one parent had a hospital diagnosis of alcoholism.
Journal ArticleDOI
Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism.
Laura J. Bierut,Stephen H. Dinwiddie,Henri Begleiter,Raymond R. Crowe,Victor Hesselbrock,John I. Nurnberger,Bernice Porjesz,Marc A. Schuckit,Theodore Reich +8 more
TL;DR: Alcohol, marijuana, and cocaine dependence and habitual smoking are all familial, and there is evidence of both common and specific addictive factors transmitted in families.
Journal ArticleDOI
Drinking problems in adopted and nonadopted sons of alcoholics
Donald W. Goodwin,Fini Schulsinger,Niels Møller,Leif Hermansen,George Winokur,Samuel B. Guze +5 more
TL;DR: It is suggested that environmental factors contributed little, if anything, to the development of alcoholism in sons of severe alcoholics, in this sample.
Journal ArticleDOI
Comorbidity of substance abuse and other psychiatric disorders in adolescents.
TL;DR: Research findings suggest a major role for substance use in the etiology and prognosis of psychiatric disorders such as affective disorders, conduct disorder and antisocial personality disorder, attention-deficit hyperactivity disorder, and anxiety disorders.
References
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Journal ArticleDOI
Clinical observations in manic-depressive disease: a quantitative study of one hundred manic-depressive patients and fifty medically sick controls
TL;DR: No evidence was found to justify the continued use of the phrase "involutional melancholia" as implying that there is anything distinctive about the depressions of women near the menopause, and many "medical" symptoms were as frequent in the manic-depressive group as in the medically sick controls.
Journal ArticleDOI
Family history studies: V. The genetics of mania.
TL;DR: In this study of the families of 59 manic-depressive, manic type probands, the predominant affective illness among the family members was depression without mania, although mania was frequent, suggesting that genetic transmission occurred by a sex-linked single or double dominant gene.
Journal ArticleDOI
Alcoholism: I. Two Types of Alcoholism in Women
TL;DR: The purpose of this paper is to describe an attempt to delineate alcoholism into nosologically homogeneous groups and to limit the present discussion to alcoholism in the female.