Alkyl-, Aryl-, Vinyl-, and Heterosubstituted Organozirconium Compounds. -Selective nucleophiles of low basicity. Preliminary communication

TLDR: In contrast to their titanium analogues, vinylzirconium reagents are stable enough to be employed. as discussed by the authors showed that aldehyde and ketone carbonylophiles of exceedingly low basicity can be solved from aldehydes and aldeheeds using trialkoxyzircimiconium chloride.

Abstract: Solutions of the title compounds are accessible from organolithium reagents and trialkoxyzirconium chloride (equation 2). In contrast to their titanium analogues, vinylzirconium reagents are stable enough to be employed. Generally, organozirconium reagents are highly selective aldehyde and ketone carbonylophiles of exceedingly low basicity (Tables 1, 2, 3 and typical procedure).