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An analysis of the time-relations of electrocardiograms

H. C. Bazett
- 01 Jan 1920 - 
- Vol. 7, pp 353-370
TLDR
In this paper, a preliminary attempt was made to determine from blood pressure records the relative influence of the heart action and of vaso-canstriction, and it was suggested that it might be necessary to estimate the duration of ventricular systole for different heart rates.
Abstract
IN a preliminary attempt (which requires considerable modification) to determine from blood-pressure records the relative influence of the heart action and of vaso-canstriction, I suggestedS that it might be necessary to estimate the duration of ventricular systole for different heart rates. In order to obtain this information a number of measurements have been made of electrocardiographic curves, including some obtained by myself and a selection of curves from Dr. T. Lewis’s collection, which he very kindly put at my disposal. Electrical records have been preferred to mechanical, because it is easier to secure accuracy, and it has been shown by many workers that as a rub the electrical and mechanical changes correspond fairly closely. Lewis ,*7 in a comparison of the heart sounds with the electrical changes, found the first sound to commence 0.011 of a second to 0.039 of a second after the commencement of Q, while the second sound started either before or after the end of T but usually within 0.01 of a second of it. WiggersYS1 working with dogs, found the mechanical systole to commence 0.03 to 0.045 after the rise of R, and to terminate 0.034 to 0.048 after the end of T, so that as a rule the two changes corresponded in duration, but he found that adrenalin shortens the duration of the mechanical change more than the electrical, and under these conditions the ventrical contrsction ended before the end of the T wave. In considering, therefore, the relative duration of systole and diastole, both electrical and mechanical records are useful, if these differences be allowed for. Walleflsgivee the following values for the durebtion of mechanical systole with different heart rates, and it will be seen that almost exactly similar figures are obtained by calculation from the formula systole = K Vcycle, where K hae 8 value of 0.343.

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The spread of the excitatory process in the vertebrate heart. parts i-v (the bird’s heart)

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TL;DR: If nonpolarisable electrodes are placed upon the body of the toad, the one contact lying on the muscle near the root of the neck in front and on the right side, while the other contact rests on the muscles in the centre of the abdominal wall, and these contacts are united to the string galvanometer in such a way that relative negativity of the cephalic contact yields in our photograph an upward excursion, then the form of the curve which is written at each cycle of the heart may be exemplified by the upper curve of fig. 1 (next page).
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Direct and reflex acceleration of the mammalian heart with some observations on the relations of the inhibitory and accelerator nerves

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The Antagonistic Action of Carbon Dioxide and Adrenalin on the Heart

TL;DR: An account of an investigation of the action of the carbon dioxide and adrenalin on the heart isolated from the nervous system is carried out.
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