Journal ArticleDOI
Anchorage-Independent Culture of Bovine Granulosa Cells: The Effects of Basic Fibroblast Growth Factor and Dibutyryl cAMP on Cell Division and Differentiation
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It is found that bovine granulosa cells were able to divide in an anchorage-independent culture system consisting of soft agar and an overlay of methylcellulose, and they developed the ultrastructural features of luteal cells.About:
This article is published in Experimental Cell Research.The article was published on 1994-04-01. It has received 98 citations till now. The article focuses on the topics: Stromal cell & Basic fibroblast growth factor.read more
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Regulation of ovarian follicular development in primates: facts and hypotheses.
TL;DR: A picture has emerged depicting the classic endocrine control of ovarian function by LH and FSH, entangled in a maze of regulatory systems hinging on cell-cell interactions between follicular cells, via action of a variety of molecules.
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Regulation of primordial follicle assembly and development
TL;DR: Observations suggest that a complex network of cell-cell interactions is required to control the primordial to primary follicle transition, which provides therapeutic targets to regulate ovarian function and treat ovarian disease.
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Theca: the forgotten cell of the ovarian follicle.
Julia Young,Alan S. McNeilly +1 more
TL;DR: While the theca is an essential component of follicle development and ovulation, it is clear that thecal cells are fundamental for follicular growth, providing all the androgens required by the developing follicle(s) for conversion into estrogens by the granulosa cells.
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Basic fibroblast growth factor induces primordial follicle development and initiates folliculogenesis
TL;DR: Basic fibroblast growth factor, like KL, appears to be a primordial follicle-inducing factor that can regulate primordial hair follicle development that directly influences female reproductive efficiency.
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Bone Morphogenetic Protein-4 Acts as an Ovarian Follicle Survival Factor and Promotes Primordial Follicle Development
TL;DR: Data suggest that BMP-4 plays an important role in promoting the survival and development of primordial follicle development and the primordial-to-primary follicle transition in the neonatal ovary.