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Antioxidant, anti-inflammatory and antiarthritic potential of Moringa oleifera Lam: An ethnomedicinal plant of Moringaceae family

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TLDR
It was found that the methanolic, aqueous and ethyl acetate extracts had exhibited the maximum in vitro antioxidant potential and showed significant inhibition in paw inflammation and prevented arthritis induced anemia and weight loss in rats in dose dependent manner.
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This article is published in South African Journal of Botany.The article was published on 2020-01-01. It has received 74 citations till now. The article focuses on the topics: Gallic acid & Kaempferol.

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Recent Advances in Drumstick (Moringa oleifera) Leaves Bioactive Compounds: Composition, Health Benefits, Bioaccessibility, and Dietary Applications

TL;DR: In this article , the authors highlight new scientific data on the moringa leaves containing nutrient and bioactive profiles, bioavailability, health benefits, and uses in various food items.
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Comparative Study of the Chemical Compositions and Antioxidant Activities of Fresh Juices from Romanian Cucurbitaceae Varieties.

TL;DR: Fruit juices obtained from four different species of the Cucurbitaceae family cultivated in Romania demonstrate very good antioxidant potential and these fruits should be further explored for their protective effect against oxidative damage.
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LC-ESI-QTOF-MS/MS characterization of phenolic compounds from Pyracantha coccinea M.Roem. and their antioxidant capacity.

TL;DR: The results of this research confirm the benefits of the P. coccinea plant as a potential source of natural antioxidants for the food and pharmaceutical industries.
Journal ArticleDOI

HPLC analysis, cytotoxicity, and safety study of Moringa oleifera Lam. (wild type) leaf extract.

TL;DR: The data of this study suggested that the plant can be safely used as a nutraceutical as well as a nutritional food and its safety in acute and long term use is validated.
References
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Journal ArticleDOI

International Consensus Guidance Statement on the Management and Treatment of IgG4-Related Disease

TL;DR: A. H. Wallace, J. L. Carruthers, S. L€ ohr, Y. Khosroshahi, Z. Chari, E. Della-Torre, L. Frulloni, H.
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The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells.

TL;DR: The modulation of iNOS, COX-2 and CRP by quercetin or kaempferol may contribute to the anti-inflammatory effects of these two structurally similar flavonoids in Chang Liver cells, via mechanisms likely to involve blockade of NF-kappaB activation and the resultant up-regulation of the pro-inflammatory genes.
Journal ArticleDOI

In vitro and in vivo antioxidant properties of different fractions of Moringa oleifera leaves

TL;DR: It is concluded that Moringa oleifera leaves possess high phenolic content and potent antioxidant properties, which may be mediated through direct trapping of the free radicals and also through metal chelation.
Journal ArticleDOI

Use of NSAIDs in treating patients with arthritis.

TL;DR: In patients with risk factors for NSAID toxicity, using the lowest dose of a drug with a short half-life only when it is needed is likely to be the safest treatment option.
Journal ArticleDOI

Antiprotease and Membrane Stabilizing Activities of Extracts of Fagara Zanthoxyloides, Olax Subscorpioides and Tetrapleura Tetraptera

TL;DR: Saline extracts of these plants stabilized human red blood cell membrane subjected to hypotonic- and heat-induced lyses and revealed that the degree of membrane stabilization was 84% for F. zanthoxyloides while T. tetraptera and O. subscorpioides exhibited 70% and63.2%, respectively.
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