Institution
University of Health Sciences Lahore
Education•Lahore, Pakistan•
About: University of Health Sciences Lahore is a education organization based out in Lahore, Pakistan. It is known for research contribution in the topics: Population & Medicine. The organization has 580 authors who have published 875 publications receiving 12238 citations.
Papers published on a yearly basis
Papers
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Harvard University1, King's College London2, University of Cape Town3, Makerere University4, Johns Hopkins University5, University of Washington6, Carter Center7, Emory University8, University of London9, World Psychiatric Association10, University of Melbourne11, Al-Quds University12, Rutgers University13, Peking University14, University of Amsterdam15, Dow University of Health Sciences16, University of Health Sciences Lahore17, University of Ibadan18, University of Liverpool19, Public Health Foundation of India20, Wellcome Trust21, University of Oxford22, South African Medical Research Council23, Groote Schuur Hospital24
1,356 citations
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TL;DR: Understanding of bacterial biofilm is important to manage and/or to eradicate biofilm-related diseases, utilizing both device-related and non-device-related infections.
Abstract: Microscopic entities, microorganisms that drastically affect human health need to be thoroughly investigated. A biofilm is an architectural colony of microorganisms, within a matrix of extracellular polymeric substance that they produce. Biofilm contains microbial cells adherent to one-another and to a static surface (living or non-living). Bacterial biofilms are usually pathogenic in nature and can cause nosocomial infections. The National Institutes of Health (NIH) revealed that among all microbial and chronic infections, 65% and 80%, respectively, are associated with biofilm formation. The process of biofilm formation consists of many steps, starting with attachment to a living or non-living surface that will lead to formation of micro-colony, giving rise to three-dimensional structures and ending up, after maturation, with detachment. During formation of biofilm several species of bacteria communicate with one another, employing quorum sensing. In general, bacterial biofilms show resistance against human immune system, as well as against antibiotics. Health related concerns speak loud due to the biofilm potential to cause diseases, utilizing both device-related and non-device-related infections. In summary, the understanding of bacterial biofilm is important to manage and/or to eradicate biofilm-related diseases. The current review is, therefore, an effort to encompass the current concepts in biofilm formation and its implications in human health and disease.
879 citations
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TL;DR: Mental health resources in countries seem to be related as much to measures of general health as to economic and developmental indicators, arguing for improved prioritisation for mental health even in low-resource settings.
501 citations
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TL;DR: A higher level of perceived stress was reported by the students and the main stressors were related to academic and psychosocial domains.
Abstract: Recently there is a growing concern about stress during undergraduate medical training. However, studies about the same are lacking from Pakistani medical schools. The objectives of our study were to assess perceived stress, sources of stress and their severity and to assess the determinants of stressed cases. A cross-sectional, questionnaire-based survey was carried out among undergraduate medical students of CMH Lahore Medical College, Pakistan during January to March 2009. Perceived stress was assessed using the perceived stress scale. A 33-item questionnaire was used to assess sources of stress and their severity. The overall response rate was 80.5% (161 out of 200 students). The overall mean perceived stress was 30.84 (SD = 7.01) and was significantly higher among female students. By logistic regression analysis, stressed cases were associated with occurrence of psychosocial (OR 5.01, 95% CI 2.44-10.29) and academic related stressors (OR 3.17 95% CI 1.52-6.68). The most common sources of stress were related to academic and psychosocial concerns. 'High parental expectations', 'frequency of examinations', 'vastness of academic curriculum', 'sleeping difficulties', 'worrying about the future', 'loneliness', 'becoming a doctor', 'performance in periodic examinations' were the most frequently and severely occurring sources of stress. There was a negative but insignificant correlation between perceived stress and academic performance (r = -0.099, p > 0.05). A higher level of perceived stress was reported by the students. The main stressors were related to academic and psychosocial domains. Further studies are required to test the association between stressed cases and gender, academic stressors and psychosocial stressors.
375 citations
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TL;DR: Mitochondrial reactive oxygen species (ROS) and Nlrp3-inflammasome activation in non-myeloid-derived cells aggravate diabetic nephropathy, and targeting the inflammasomes may be a potential therapeutic approach to diabetic neophropathy.
309 citations
Authors
Showing all 591 results
Name | H-index | Papers | Citations |
---|---|---|---|
Muhammad Imran | 94 | 3053 | 51728 |
Muhammad Riaz | 58 | 934 | 15927 |
Sheikh Riazuddin | 58 | 259 | 10934 |
Saima Riazuddin | 47 | 137 | 7387 |
J. Fielding Hejtmancik | 47 | 175 | 6890 |
Nasir Mahmood | 45 | 245 | 9614 |
Shaheen N. Khan | 39 | 110 | 5986 |
Muhammad Kashif | 33 | 349 | 3699 |
Muhammad Shahzad | 31 | 228 | 4323 |
Abdul Ghaffar | 28 | 52 | 1898 |
Shagufta Khaliq | 27 | 65 | 2242 |
Muhammad Wakil Shahzad | 26 | 139 | 2319 |
Javed Akram | 24 | 89 | 1780 |
Zafar Iqbal | 24 | 139 | 2144 |
Saqib Mahmood | 22 | 87 | 1796 |