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Journal ArticleDOI

Antioxidative activity of natural products from plants.

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TLDR
A variety of flavonoids, lignans, an alkaloid, a bisbenzyl, coumarins and terpenes isolated from Chinese herbs was tested for antioxidant activity as reflected in the ability to inhibit lipid peroxidation in rat brain and kidney homogenates and rat erythrocyte hemolysis.
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This article is published in Life Sciences.The article was published on 2000-01-14. It has received 497 citations till now. The article focuses on the topics: Lipid peroxidation & Kidney metabolism.

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Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships.

TL;DR: The diversity and multiple mechanisms of flavonoid action, together with the numerous methods of initiation, detection and measurement of oxidative processes in vitro and in vivo offer plausible explanations for existing discrepancies in structure-activity relationships.
Journal ArticleDOI

Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer.

TL;DR: Traditional Chinese medicinal plants associated with anticancer might be potential sources of potent natural antioxidants and beneficial chemopreventive agents, and contain significantly higher levels of phenolics than common vegetables and fruits.
Journal ArticleDOI

Toxicity of lead: A review with recent updates.

TL;DR: A comprehensive account of recent updates describing health effects of lead exposure, relevant biomarkers and mechanisms involved in lead toxicity, and updates the readers about recent advances in chelation therapy and newer therapeutic strategies, like nanoencapsulation, to treat lead induced toxic manifestations are provided.
Journal ArticleDOI

Antioxidant activity and total phenolics of edible mushroom extracts

TL;DR: Methanol and water crude extracts from Shiitake mushroom (Lentinus edodes) and straw mushroom (Volvariella volvacea) were investigated for their antioxidant capacity in three different assays, namely, β-carotene and linoleic acid system, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, and inhibition of hemolysis of rat erythrocyte induced by peroxyl radicals.
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Determination of flavone, flavonol, and flavanone aglycones by negative ion liquid chromatography electrospray ion trap mass spectrometry.

TL;DR: The negative ion mode was a powerful complementary tool of the positive ion mode for the structural characterization of flavonoid aglycones by ESI-MS/MS, and several structurally informative anions appeared highly specific of thenegative ion mode.
References
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Book

Free radicals in biology and medicine

TL;DR: 1. Oxygen is a toxic gas - an introduction to oxygen toxicity and reactive species, and the chemistry of free radicals and related 'reactive species'
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How to characterize a biological antioxidant.

TL;DR: A review of the pro-oxidant and anti-Oxidant properties of ascorbic acid that have been reported in the literature leads to the conclusion that this compound acts as an antioxidant in vivo under most circumstances.
Journal ArticleDOI

Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation.

TL;DR: It was concluded that rutin and quercetin are able to suppress free radical processes at three stages: the formation of superoxide ion, the generation of hydroxyl (or cryptohydroxyl) radicals in the Fenton reaction and theformation of lipid peroxy radicals.
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Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol

TL;DR: The data suggest that thymol, carvacrol and 6-gingerol possess useful antioxidant properties and may become important in the search for 'natural' replacements for 'synthetic' antioxidant food additives.
Journal Article

Chemoprevention of Colon Carcinogenesis by Dietary Curcumin, a Naturally Occurring Plant Phenolic Compound

TL;DR: Investigation of the chemopreventive action of dietary curcumin on azoxymethane-induced colon carcinogenesis and also the modulating effect of this agent on the colonic mucosal and tumor phospholipase A2, phospholIPase C gamma 1, lipoxygenase, and cyclo oxygengenase activities in male F344 rats indicates that dietary administration ofCurcumin significantly inhibited incidence of colon adenocarcinomas.
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