Association between a Novel Human Coronavirus and Kawasaki Disease
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TLDR
Evidence of a novel human coronavirus, designated “New Haven coronav virus” (HCoVNH), in respiratory secretions from a 6-month-old infant with classic Kawasaki disease is identified and data suggest that HCoV-NH infection is associated with Kaw Osaka disease.Citations
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An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study.
Lucio Verdoni,Angelo Mazza,Annalisa Gervasoni,Laura Martelli,Maurizio Ruggeri,Matteo Ciuffreda,Ezio Bonanomi,Lorenzo D'Antiga +7 more
TL;DR: Children diagnosed after the SARS-CoV-2 epidemic began showed evidence of immune response to the virus, were older, had a higher rate of cardiac involvement, and features of MAS, and a similar outbreak of Kawasaki-like disease is expected in countries involved in the SEMS epidemic.
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Coronavirus Pathogenesis and the Emerging Pathogen Severe Acute Respiratory Syndrome Coronavirus
TL;DR: The data gathered on the animal coronaviruses continue to be helpful in understanding SARS-CoV, and the progress in vaccine development and antiviral therapies is discussed.
Journal ArticleDOI
Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study.
Julie Toubiana,Julie Toubiana,Clément Poirault,Alice Corsia,Fanny Bajolle,Jacques Fourgeaud,François Angoulvant,Agathe Debray,Romain Basmaci,Elodie Salvador,Sandra Biscardi,Pierre Frange,Martin Chalumeau,Jean-Laurent Casanova,Jean-Laurent Casanova,Jérémie F. Cohen,Slimane Allali +16 more
TL;DR: An unusually high proportion of the affected children and adolescents had gastrointestinal symptoms, Kawasaki disease shock syndrome, and were of African ancestry in this study, suggesting that the ongoing outbreak of Kawasaki-like multisystem inflammatory syndrome in the Paris area might be related to SARS-CoV-2.
Journal ArticleDOI
Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry
TL;DR: It is shown that SARS-CoV shares its receptor ACE2 with HCoV-NL63, which suggests that highly pathogenic variants have ample opportunity to evolve, underlining the need for vaccines against HCoVs.
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COVID-19 and multisystem inflammatory syndrome in children and adolescents.
Li Jiang,Kun Tang,Michael Levin,Omar Irfan,Shaun K. Morris,Karen M. Wilson,Jonathan D. Klein,Zulfiqar A Bhutta +7 more
TL;DR: In this paper, the authors reviewed the epidemiology, causes, clinical features, and current treatment protocols for multisystem inflammatory syndrome in children and adolescents associated with COVID-19.
References
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TL;DR: The identification and characterization of a not previously recognized coronavirus obtained from an 8-mo-old boy suffering from pneumonia is described, revealing that it is most closely related to porcine epidemic diarrhea virus and HCoV 229E.