Association between serum magnesium and common complications of diabetes mellitus.
TLDR
Low concentration of serum magnesium and four common diabetic complications – diabetic retinopathy, diabetic nephropathy, diabetic neuropathy and diabetic macroangiopathy – exists association, but no obvious correlation with other comorbidities like hypertension.Abstract:
Background Magnesium ion, as important cation in the human body, involved in various enzymatic reactions, glucose transport and insulin release. Now diabetes mellitus and diabetic complications have become important public health problems around the world. Objective This paper explores the association between concentration levels of serum magnesium and common complications and comorbidities of diabetes mellitus and other biochemical indexes. Methods There are 1217 eligible patients selected from 14,317 cases of diabetic hospitalization patients from January 2010 to December 2011. Random forest algorithm was applied to assess the importance of various biochemical indexes and to perform diabetic complications prediction. Results The research results showed that low concentration of serum magnesium and four common diabetic complications - diabetic retinopathy, diabetic nephropathy, diabetic neuropathy and diabetic macroangiopathy - exists association, but no obvious correlation with other comorbidities like hypertension. Conclusions The specific factors of four common diabetic complications were selected from the biochemical indexes to provide a reference direction for further research.read more
Citations
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Role of Magnesium in Type 2 Diabetes Mellitus.
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Vitreous humor endogenous compounds analysis for post-mortem forensic investigation.
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Developing a random forest classifier for predicting the depression and managing the health of caregivers supporting patients with Alzheimer's Disease.
TL;DR: It was proved that the developed random forest-based App for predicting and managing the depression of dementia caregivers used an algorithm that has a high predictive power.
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Serum Magnesium Is Inversely Associated With Heart Failure, Atrial Fibrillation, and Microvascular Complications in Type 2 Diabetes.
Lynette J. Oost,Amber A W A van der Heijden,Emma A. Vermeulen,Caro Bos,Petra J. M. Elders,Roderick C. Slieker,Roderick C. Slieker,Steef Kurstjens,Steef Kurstjens,Miranda van Berkel,Joost G. J. Hoenderop,Cees J. Tack,Joline W.J. Beulens,Jeroen H. F. de Baaij +13 more
TL;DR: In this article, the association of serum magnesium (Mg2+) with macrovascular disease and mortality (acute myocardial infarction [AMI], coronary heart disease [CHD], heart failure [HF], cerebrovascular accident [CVA), and peripheral arterial disease [PAD]), atrial fibrillation (AF), and diabetic foot) using Cox regression, adjusted for confounders.
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Overview of dietary supplements on patients with type 2 diabetes.
TL;DR: The available evidence is insufficient to create a definite conclusion that nutritional supplements including chromium, n-3 PUFAs, vitamin D, zinc and magnesium might be beneficial for the prevention and treatment of T2DM and therefore, the general recommendation to use these supplements in the management of diabetes cannot be justified.
References
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Journal ArticleDOI
Random Forests
TL;DR: Internal estimates monitor error, strength, and correlation and these are used to show the response to increasing the number of features used in the forest, and are also applicable to regression.
Book ChapterDOI
Random Forest for Bioinformatics
TL;DR: The Random Forest technique, which includes an ensemble of decision trees and incorporates feature selection and interactions naturally in the learning process, is a popular choice because it is nonparametric, interpretable, efficient, and has high prediction accuracy for many types of data.
Journal ArticleDOI
Associations of serum and dietary magnesium with cardiovascular disease, hypertension, diabetes, insulin, and carotid arterial wall thickness: The aric study
Jing Ma,Aaron R. Folsom,Sandra L. Melnick,John H. Eckfeldt,A. Richey Sharrett,Azmi A. Nabulsi,Richard G. Hutchinson,Patricia Metcalf +7 more
TL;DR: Low serum and dietary Mg may be related to the etiologies of CVD, hypertension, diabetes, and atherosclerosis.
Journal ArticleDOI
Role of magnesium in insulin action, diabetes and cardio-metabolic syndrome X.
Mario Barbagallo,Ligia J. Dominguez,Antonio Galioto,Ferlisi A,Calogero Cani,Loriano Malfa,Pineo A,Adele Busardo,Giuseppe Paolisso +8 more
TL;DR: A growing body of studies suggest that intracellular Mg may play a key role in modulating insulin-mediated glucose uptake and vascular tone, and it is suggested that a reduced intrace cellular Mg concentration might be the missing link helping to explain the epidemiological association between NIDDM and hypertension.
Journal ArticleDOI
Magnesium metabolism in type 2 diabetes mellitus, metabolic syndrome and insulin resistance
TL;DR: Benefits of Mg supplementation on metabolic profile in diabetic subjects have been found in most, but not all clinical studies, and larger prospective studies are needed to support the potential role of dietary Mg supplements as a possible public health strategy in diabetes risk.