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Biochemistry and Molecular Biology The Shikimate Pathway - A Metabolic Tree with Many Branches
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The article was published on 1990-01-01 and is currently open access. It has received 635 citations till now. The article focuses on the topics: Shikimate pathway.read more
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The shikimate pathway.
Klaus M. Herrmann,Lisa M. Weaver +1 more
TL;DR: The shikimate pathway links metabolism of carbohydrates to biosynthesis of aromatic compounds, the precursor of the aromatic amino acids and many aromatic secondary metabolites, and is the sole target for the herbicide glyphosate.
Journal ArticleDOI
The shikimate pathway and aromatic amino acid biosynthesis in plants.
TL;DR: The pathway organization and the transcriptional/posttranscriptional regulation of the AAA biosynthetic network is summarized and the current limited knowledge of the subcellular compartmentalization and the metabolite transport involved in the plant AAA pathways is identified.
Journal ArticleDOI
Mycosporine-Like Amino Acids and Related Gadusols: Biosynthesis, Accumulation, and UV-Protective Functions in Aquatic Organisms
TL;DR: Probing the regulation and biosynthesis of MAAs provides insight to the physiological evolution and utility of UV protection and of biochemically associated antioxidant defenses.
Journal ArticleDOI
The Shikimate Pathway: Early Steps in the Biosynthesis of Aromatic Compounds.
TL;DR: This review gives a short overview of the shikimate pathway and briefly introduces the seven enzymes that catalyze the sequential steps of the pathway, and discusses some regulatory features of severa1 of the enzymes.
Journal ArticleDOI
Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail
Ernst Schönbrunn,Susanne Eschenburg,Wendy A. Shuttleworth,John V. Schloss,Nikolaus Amrhein,Jeremy N.S. Evans,Wolfgang Kabsch +6 more
TL;DR: The elucidation of the active site of EPSP synthase and especially of the binding pattern of glyphosate provides a valuable roadmap for engineering new herbicides and herbicide-resistant crops, as well as new antibiotic and antiparasitic drugs.
References
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Purification and properties
TL;DR: It is an opioid agonist on the guinea pig myenteric plexus-longitudinal muscle preparation, and on the mouse vas deferens, and it binds to opiate receptors in homogenates of Guinea pig brain.
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Distribution of isoprenoid quinone structural types in bacteria and their taxonomic implication.
M D Collins,D Jones +1 more
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Prediction of the Occurrence of the ADP-binding βαβ-fold in Proteins, Using an Amino Acid Sequence Fingerprint
TL;DR: An amino acid sequence “fingerprint” has been derived that can be used to test if a particular sequence will fold into aβαβ-unit with ADP-binding properties, which is in fact a set of 11 rules describing the type of amino acid that should occur at a specific position in a peptide fragment.