Journal ArticleDOI
Biomarkers in heart failure. Preface.
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TLDR
The next logical step is to obtain a profile using the seven classes of biomarker described in this issue, which should provide not only a more accurate risk stratification, but it may provide clues to the pathophysiology of HF in any given patient and point the way to individualized therapy.About:
This article is published in Heart Failure Clinics.The article was published on 2009-10-01. It has received 13 citations till now. The article focuses on the topics: Heart failure.read more
Citations
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Journal ArticleDOI
Urinary proteomic diagnosis of coronary artery disease: identification and clinical validation in 623 individuals.
Christian Delles,Eric Schiffer,Constantin von zur Mühlen,Karlheinz Peter,Peter Rossing,Hans-Henrik Parving,Jane A. Dymott,Ulf Neisius,Lukas Zimmerli,Janet K. Snell-Bergeon,David M. Maahs,Roland E. Schmieder,Harald Mischak,Anna F. Dominiczak +13 more
TL;DR: Urinary proteomics identifies CAD with high confidence and might also be useful for monitoring the effects of therapeutic interventions.
Journal ArticleDOI
Plasma norepinephrine is an independent predictor of vascular endothelial function with aging in healthy women
TL;DR: The first evidence that EDD is inversely related to sympathetic activity, as assessed by PNE, among healthy adults varying in age is provided, suggesting that sympathetic nervous system activity may be a key factor involved in the modulation of vascular endothelial function with aging in women.
Journal ArticleDOI
The inflammatory biomarker YKL-40 as a new prognostic marker for all-cause mortality in patients with heart failure
Marina Harutyunyan,Michael Christiansen,Julia S. Johansen,Lars Køber,Christian Torp-Petersen,Jens Kastrup +5 more
TL;DR: Serum YKL-40 is significantly associated with all-cause mortality in patients with HF and could potentially be a new prognostic biomarker in these patients.
Journal ArticleDOI
Potential application of the oxidative nucleic acid damage biomarkers in detection of diseases
Cheng Guo,Peili Ding,Cong Xie,Chenyang Ye,Minfeng Ye,Chi Pan,Xiaoji Cao,Suzhan Zhang,Shu Zheng +8 more
TL;DR: The relationship of oxidative nucleic acid damage and development of various diseases including cancers including cancers, lung cancer, epithelial ovarian carcinoma, esophageal squamous cell carcinomas, neurodegenerative disorders and chronic diseases were reviewed.
Journal ArticleDOI
New Management Strategies in Heart Failure
TL;DR: This review will summarize newer drugs currently being used in the treatment of heart failure, as well as newer strategies increasingly explored for their utility during the stages of the heart failure syndrome.
References
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Journal ArticleDOI
Use of Multiple Biomarkers to Improve the Prediction of Death from Cardiovascular Causes
Björn Zethelius,Lars Berglund,Johan Sundström,Erik Ingelsson,Samar Basu,Anders Larsson,Per Venge,Johan Ärnlöv +7 more
TL;DR: It is suggested that in elderly men with or without prevalent cardiovascular disease, the simultaneous addition of several biomarkers of cardiovascular and renal abnormalities substantially improves the risk stratification for death from cardiovascular causes beyond that of a model that is based only on established risk factors.
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Multimarker Approach to Risk Stratification in Non-ST Elevation Acute Coronary Syndromes: Simultaneous Assessment of Troponin I, C-Reactive Protein, and B-Type Natriuretic Peptide
Marc S. Sabatine,David A. Morrow,James A. de Lemos,C. Michael Gibson,Sabina A. Murphy,Nader Rifai,Carolyn H. McCabe,Elliott M. Antman,Christopher P. Cannon,Eugene Braunwald +9 more
TL;DR: Troponin, CRP, and BNP each provide unique prognostic information in patients with ACS and a simple multimarker strategy that categorizes patients based on the number of elevated biomarkers at presentation allows risk stratification over a broad range of short- and long-term major cardiac events.
Journal ArticleDOI
Prognostic Value of Very Low Plasma Concentrations of Troponin T in Patients With Stable Chronic Heart Failure
Roberto Latini,Roberto Latini,Serge Masson,Inder S. Anand,Emil Missov,Marjorie Carlson,Tarcisio Vago,Laura Angelici,Simona Barlera,Giovanni Parrinello,Aldo P. Maggioni,Gianni Tognoni,Jay N. Cohn +12 more
TL;DR: In this large population of patients with HF, detectable cTnT predicts adverse outcomes in chronic HF by the highly sensitive assay, which retains a prognostic value at previously undetectable concentrations.
Journal ArticleDOI
Cardiac Troponin I Is Associated With Impaired Hemodynamics, Progressive Left Ventricular Dysfunction, and Increased Mortality Rates in Advanced Heart Failure
TL;DR: cTnI may be a novel, useful tool in identifying patients with HF who are at increased risk for progressive ventricular dysfunction and death, and used in conjunction with BNP further improved prognostic value.
Journal ArticleDOI
Measurement of the Interleukin Family Member ST2 in Patients With Acute Dyspnea: Results From the PRIDE (Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department) Study
James L. Januzzi,W. Frank Peacock,Alan S. Maisel,Claudia U. Chae,Robert L. Jesse,Aaron L. Baggish,Michelle L. O'Donoghue,Rahul Sakhuja,Annabel A. Chen,Roland R.J. van Kimmenade,Kent B. Lewandrowski,Donald M. Lloyd-Jones,Alan H.B. Wu +12 more
TL;DR: Among dyspneic patients with and without acute HF, ST2 concentrations are strongly predictive of mortality at 1 year and might be useful for prognostication when used alone or together with NT-proBNP.