Boswellia Serrata, A Potential Antiinflammatory Agent: An Overview
TLDR
Gum-resin extracts of Boswellia serrata have been traditionally used in folk medicine for centuries to treat various chronic inflammatory diseases.Abstract:
The resin of Boswellia species has been used as incense in religious and cultural ceremonies and in medicines since time immemorial. Boswellia serrata (Salai/Salai guggul), is a moderate to large sized branching tree of family Burseraceae (Genus Boswellia), grows in dry mountainous regions of India, Northern Africa and Middle East. Oleo gum-resin is tapped from the incision made on the trunk of the tree and is then stored in specially made bamboo basket for removal of oil content and getting the resin solidified. After processing, the gum-resin is then graded according to its flavour, colour, shape and size. In India, the States of Andhra Pradesh, Gujarat, Madhya Pradesh, Jharkhand and Chhattisgarh are the main source of Boswellia serrata. Regionally, it is also known by different names. The oleo gum-resins contain 30-60% resin, 5-10% essential oils, which are soluble in the organic solvents, and the rest is made up of polysaccharides. Gum-resin extracts of Boswellia serrata have been traditionally used in folk medicine for centuries to treat various chronic inflammatory diseases. The resinous part of Boswellia serrata possesses monoterpenes, diterpenes, triterpenes, tetracyclic triterpenic acids and four major pentacyclic triterpenic acids i.e. β-boswellic acid, acetyl-β-boswellic acid, 11-keto-β-boswellic acid and acetyl-11-keto-β-boswellic acid, responsible for inhibition of pro-inflammatory enzymes. Out of these four boswellic acids, acetyl-11-keto-β-boswellic acid is the most potent inhibitor of 5-lipoxygenase, an enzyme responsible for inflammation.read more
Citations
More filters
Journal ArticleDOI
Trease and Evans' pharmacognosy
TL;DR: Bargaining with reading habit is no need, reading is not kind of something sold that you can take or not and how can you bargain with the thing that has many benefits for you?
Journal ArticleDOI
Effective Medicinal Plant in Cancer Treatment, Part 2: Review Study.
Wesam Kooti,Karo Servatyari,Masoud Behzadifar,Majid Asadi-Samani,Fatemeh. Sadeghi,Bijan Nouri,Hadi Zare Marzouni +6 more
TL;DR: Herbal extracts have antioxidant compounds that can induce apoptosis and inhibit cell proliferation by the investigated mechanisms, according to results of this study.
Journal ArticleDOI
An Update on Pharmacological Potential of Boswellic Acids against Chronic Diseases.
Nand Kishor Roy,Dey Parama,Kishore Banik,Devivasha Bordoloi,Amrita Khwairakpam Devi,Krishan Kumar Thakur,Ganesan Padmavathi,Mehdi Shakibaei,Lu Fan,Gautam Sethi,Ajaikumar B. Kunnumakkara +10 more
TL;DR: The present review is an attempt to demonstrate the diverse pharmacological uses of BA, along with its underlying molecular mechanism of action against different ailments, and the roadblocks associated with the pharmacokinetics and bioavailability of this promising compound.
Journal ArticleDOI
New molecular and biochemical insights of doxorubicin-induced hepatotoxicity.
TL;DR: Certain substances such as extracts from medicinal plants, natural products, and chemical substances have been shown to produce an alleviating effect against the doxorubicin-induced hepatotoxicity are also discussed.
Journal ArticleDOI
The potential role of boswellic acids in cancer prevention and treatment
Nand Kishor Roy,Anindita Deka,Devivasha Bordoloi,Srishti Mishra,Alan Prem Kumar,Gautam Sethi,Ajaikumar B. Kunnumakkara +6 more
TL;DR: This review projects the pieces of evidence that reveal the potential of boswellic acid as a suitable candidate that can be appropriately developed and designed into a promising anti-cancer drug.
References
More filters
Book
Encyclopedia of Common Natural Ingredients: Used in Food, Drugs, and Cosmetics
Albert Y. Leung,Steven Foster +1 more
TL;DR: In this article, the authors present an overview of natural ingredients and their applications in the field of chemical engineering, including the following categories: Natural Ingredients, Chemical Index, and Chemical Index.
Journal ArticleDOI
Trease and Evans' pharmacognosy
TL;DR: Bargaining with reading habit is no need, reading is not kind of something sold that you can take or not and how can you bargain with the thing that has many benefits for you?
Book
Textbook of pharmacognosy
TL;DR: The aim of this book is to contribute towards the humanizing of pharmacognosy and its application in the field of medicine.