Journal ArticleDOI
Brain monoamines and free choice ethanol consumption in rats.
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TLDR
The results indicate that disrupting the balance between the monoamine neuro-transmitter systems with the neurotoxins alters the free choiceanol consumption of rats but that prior chronic exposure to ethanol also changes free choice ethanol consumption in the absence of any permanent change in monoamine levels.About:
This article is published in Drug and Alcohol Dependence.The article was published on 1978-07-01. It has received 52 citations till now. The article focuses on the topics: Monoamine neurotransmitter.read more
Citations
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Serotonin and alcohol intake, abuse, and dependence: Findings of animal studies.
TL;DR: It is concluded that serotonin mediates ethanol intake as a part of its larger role in behavior modulation, such that increases in serotonergic functioning decrease ethanol intake, and decreased serotonergy functioning increases ethanol intake.
REVIEW ARTICLE Serotonin and Alcohol Intake, Abuse, and Dependence: Findings of Animal Studies
TL;DR: In this article, the effects of serotonergic manipulations on the intake of alcohol, and the effect of acute and chronic alcohol intake, as well as the withdrawal of chronic alcohol, on the Serotonergic system were investigated.
Journal ArticleDOI
There and Back Again: A Tale of Norepinephrine and Drug Addiction
TL;DR: The purpose of this review is to synthesize the new data linking NE to critical aspects of DA signaling and drug addiction, with a focus on psychostimulants (eg, cocaine), opiates, and alcohol.
Journal ArticleDOI
The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement.
TL;DR: In this paper, the role of mesolimbic dopamine in ethanol-seeking behavior was investigated in the nucleus accumbens (NAcc), which is subdivided into core and shell subregions.
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Alcohol self-administration: further examination of the role of dopamine receptors in the nucleus accumbens.
TL;DR: D1-like and D2-like receptors in the N Acc interact in the regulation of ethanol self-administration in a manner similar to their interactive regulation of other behaviors, suggesting that some intermediate level of D1 activation is required to observe the D2 effect.
References
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Journal ArticleDOI
Stereotaxic mapping of the monoamine pathways in the rat brain.
TL;DR: The ascending monoamine pathways in the rat brain are demonstrated by the pile up of fluorescent material occurring in the axons after various types of lesions, indicating a unique role for the locus coeruleus in influencing the activity of the entire brain.
Journal ArticleDOI
Opiate Receptor: Demonstration in Nervous Tissue
TL;DR: Tritiated naloxone, a powerful opiate antagonist, specifically binds to an opiate receptor of mammalian brain and guinea pig intestine that closely parallels their pharmacological potency.
Journal ArticleDOI
The Fetal Alcohol Syndrome
TL;DR: The frequency (43%) of adverse outcome of pregnancy for chronic alcoholic women suggests that serious consideration be given to early termination of pregnancy in severely Chronic alcoholic women.
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