Journal ArticleDOI
Burst spinal cord stimulation for limb and back pain.
TLDR
In contrast to tonic stimulation, burst stimulation was able to provide pain relief without the generation of paresthesias, permitting them to use a double-blinded placebo controlled approach.About:
This article is published in World Neurosurgery.The article was published on 2013-11-01. It has received 317 citations till now. The article focuses on the topics: Referred pain & Back pain.read more
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Differential Modulation of Dorsal Horn Neurons by Various Spinal Cord Stimulation Strategies.
TL;DR: In this paper, the authors examined whether low-intensity 10 kHz spinal cord stimulation (SCS) strategies at intensities below sensory thresholds would modulate spinal dorsal horn (DH) neuronal function in a neuron type-dependent manner.
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The Use of Spinal Cord Stimulation/Neuromodulation in the Management of Chronic Pain
TL;DR: Clinically, spinal cord stimulation (SCS)/neuromodulation has been used in the management of chronic pain (especially spine-related pain) for more than two decades, and high-frequency stimulation, burst stimulation, tonic stimulation with broader paddles, and new stimulation targets such as the dorsal root ganglion hold promise for improved pain management via neuromodulations moving forward.
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Spinal cord stimulation for the treatment of neuropathic pain: expert opinion and 5-year outlook
TL;DR: There are still significant limitations in the body of reviewed evidence and it is suggested that long-term data beyond 24 months are lacking in the literature and the sham effect looms as important concepts to address in the future in spite of the existing novel stimulation paradigms.
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Dynamic Computational Model of the Human Spinal Cord Connectome.
TL;DR: A draft connectivity map of the human spinal cord connectome is constructed, providing a template for the many calibrations of specialized behavior to be overlaid on it and the basis for an initial computational model, used to perform a detailed study of spinal cord stimulation for analgesia.
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Potential Therapeutic Effect of Low Amplitude Burst Spinal Cord Stimulation on Pain.
TL;DR: The SUNBURST Study demonstrated that burst spinal cord stimulation was superior compared to tonic stimulation in suppressing chronic intractable pain, but when on burst stimulation, participants preferred lower to higher amplitudes, leading to the hypothesis that lower burst amplitudes will correlate with lower pain scores while higher Amplitudes will be associated with higher pain scores.
References
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How do you feel? Interoception: the sense of the physiological condition of the body.
TL;DR: Functional anatomical work has detailed an afferent neural system in primates and in humans that represents all aspects of the physiological condition of the physical body that might provide a foundation for subjective feelings, emotion and self-awareness.
Journal Article
Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details.
TL;DR: The technical details of the method are presented, allowing researchers to test, check, reproduce and validate the new method, and a solution reported here yields images of standardized current density with zero localization error.
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Pain affect encoded in human anterior cingulate but not somatosensory cortex.
TL;DR: These findings provide direct experimental evidence in humans linking frontal-lobe limbic activity with pain affect, as originally suggested by early clinical lesion studies.
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Functional imaging of brain responses to pain. A review and meta-analysis (2000).
TL;DR: Data suggest that hemodynamic responses to pain reflect simultaneously the sensory, cognitive and affective dimensions of pain, and that the same structure may both respond to pain and participate in pain control.