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Journal ArticleDOI

Burst spinal cord stimulation for limb and back pain.

TLDR
In contrast to tonic stimulation, burst stimulation was able to provide pain relief without the generation of paresthesias, permitting them to use a double-blinded placebo controlled approach.
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This article is published in World Neurosurgery.The article was published on 2013-11-01. It has received 317 citations till now. The article focuses on the topics: Referred pain & Back pain.

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Citations
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Journal ArticleDOI

The Appropriate Use of Neurostimulation of the Spinal Cord and Peripheral Nervous System for the Treatment of Chronic Pain and Ischemic Diseases: The Neuromodulation Appropriateness Consensus Committee

TL;DR: The Neuromodulation Appropriateness Consensus Committee (NACC) of the International Neurodulation Society evaluated evidence regarding the safety and efficacy of neurostimulation to treat chronic pain, chronic critical limb ischemia, and refractory angina and recommended appropriate clinical applications.
Journal ArticleDOI

Success Using Neuromodulation With BURST (SUNBURST) Study: Results From a Prospective, Randomized Controlled Trial Using a Novel Burst Waveform.

TL;DR: The purpose of the multicenter, randomized, unblinded, crossover Success Using Neuromodulation with BURST (SUNBURST) study was to determine the safety and efficacy of a device delivering both traditional tonic stimulation and burst stimulation to patients with chronic pain of the trunk and/or limbs.
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Reversible nerve conduction block using kilohertz frequency alternating current.

TL;DR: The features and clinical applications of balanced‐charge kilohertz frequency alternating currents (KHFAC) are reviewed and there is a significant increase in interest in KHFAC block, both scientifically and clinically.
References
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Journal ArticleDOI

Pain relief by spinal cord stimulation involves serotonergic mechanisms: An experimental study in a rat model of mononeuropathy

TL;DR: There is evidence that the spinal 5‐HT system plays an important role in the mode of action of SCS involving the activation of descending serotonergic pathways that may inhibit spinal nociceptive processing partially via a GABAergic link.
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Nociceptive behavior in animal models for peripheral neuropathy: spinal and supraspinal mechanisms.

TL;DR: It is speculated that neuropathic pain, like extrapyramidal motor syndromes, reflects a disorder in the processing of somatosensory information.
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Membrane Properties of Physiologically Classified Rat Dorsal Horn Neurons In Vitro: Correlation with Cutaneous Sensory Afferent Input

TL;DR: Data indicate, firstly, that dorsal horn neurons possess heterogeneous membrane properties and, secondly, that a relationship exists between a neuron's biophysical profile and its excitatory or inhibitory response to peripheral cutaneous afferent stimulation.
Journal ArticleDOI

Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.

TL;DR: It is suggested that both supraspinal and segmental mechanisms are activated by SCS, and that in this model with DC lesions, rostral and caudal stimulations may activate different synaptic circuitries and transmitter systems.
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Functional magnetic resonance imaging of cerebral activation during spinal cord stimulation in failed back surgery syndrome patients

TL;DR: Functional magnetic resonance imaging was performed on eight patients suffering from failed back surgery syndrome who were also being treated with SCS for severe pain in their legs and lower back to evaluate the effects of SCS on the processing of acute experimental pain.
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