Journal ArticleDOI
Calculated intra- and extracellular PO2 gradients in heavily working red muscle.
K. Groebe,G. Thews +1 more
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A recently introduced three-dimensional analytical model of O 2 diffusion to heavily working muscle that considers myoglobin-facilitated O2 diffusion inside the muscle fiber and a carrier-free layer separating erythrocytes and fiber is able to furnish the following new insights in O2 supply to red muscle at high performance.Abstract:
A recently introduced three-dimensional analytical model of O2 diffusion to heavily working muscle that considers myoglobin-facilitated O2 diffusion inside the muscle fiber and a carrier-free layer...read more
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Oxygen Uptake Kinetics
David C. Poole,Andrew M. Jones +1 more
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Journal ArticleDOI
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TL;DR: The data suggest that during submaximal metabolic rates, the relationship between O2 extraction is dependent on fibre type (at least in the muscles studied herein), such that muscles comprised of fast‐twitch fibres display a greater fractional O1 extraction than their slow‐twitch counterparts.
Journal ArticleDOI
Skeletal muscle capillary hemodynamics from rest to contractions: implications for oxygen transfer.
TL;DR: It is concluded that contraction-induced alterations in capillary RBC flux and distribution augment both convective and diffusive mechanisms for blood-myocyte O(2) transfer.
Journal ArticleDOI
Role of endothelium-derived nitric oxide in the regulation of cardiac oxygen metabolism: implications in health and disease.
TL;DR: The role of NO in the control of mitochondrial respiration, with special emphasis on its effect on cardiac metabolism, is critically evaluated.