Journal ArticleDOI
Carcinogenic nitrogen compounds. XLVII. Gamma-carbolines and 2,10-diaza-anthracenes isosteric with benzocarbazoles and benzacridines.
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This article is published in Journal of The Chemical Society-perkin Transactions 1.The article was published on 1965-01-01. It has received 7 citations till now.read more
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Synthesis and DNA Binding Properties of γ-Carbolinium Derivatives and Benzologues
Andrés Molina,Juan J. Vaquero,José L. García-Navío,Julio Alvarez-Builla,Beatriz de Pascual-Teresa,Federico Gago,and María M. Rodrigo,Milagros Ballesteros +7 more
TL;DR: In this article, the DNA-binding properties of the resulting cationic systems were examined using UV−vis spectroscopy, viscometric determinations, and molecular modeling techniques, and the tetracyclic cations were transformed into bis-salts by means of a diethyl bispiperidine rigid chain and a more flexible polyamide linker.
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Synthesis of isocryptolepine, an alkaloid fromCryptolepis sanguinolenta
TL;DR: Isocryptolepine, an alkaloid recently isolated from the roots ofCryptolepis sanguinotenta, was synthesized by selective methylation at the N(5) atom of 11H-indolo(3,2-c]quinoline with excess Mel in toluene.
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Isolation and synthesis of cryptosanguinolentine (isocryptolepine), a naturally-occurring bioactive indoloquinoline alkaloid
TL;DR: Cryptosanguinolentine (isocryptolepine) is one of the minor naturallyoccurring monomeric indoloquinoline alkaloids, isolated from the West African climbing shrub Cryptolepis sanguinola as discussed by the authors.
Journal ArticleDOI
Gold-catalyzed nucleophilic tandem cyclizations of tetraethynylethene derivatives
Johannes Schädlich,Marcel Wieteck,Matthias Rudolph,Mie Højer Larsen,A. Stephen K. Hashmi,A. Stephen K. Hashmi +5 more
TL;DR: In this paper, a fourfold nucleophilic tandem cyclization extended π-systems like carbazolocarbazoles are accessible in high efficiency and in complete atom economy.
Journal Article
SYNTHESIS OF NOVEL γ-CARBOLINE DERIVATIVES AND THEIR IN SILICO STUDIES ON 5HT1, H1 AND CCR2 ANTAGONIST RECEPTORS
TL;DR: In this article, the synthesis of novel γ-carbolinesulfonamides, amides and tertiary amines 5a-l from compound 4 as a key intermediate was carried out by taking mixture of 1 equiv. of N-Boc piperidone and 0.25 equiv of TP as catalyst.