Journal ArticleDOI
Cat’s claw inhibits TNFα production and scavenges free radicals: role in cytoprotection
Manuel Sandoval,Randi M Charbonnet,Nataly N. Okuhama,Jarod Roberts,Zdenka Krenova,Ann Marie Trentacosti,Mark J S Miller +6 more
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TLDR
The primary mechanism for cat's claw anti-inflammatory actions appears to be immunomodulation via suppression of TNFalpha synthesis, which is an effective antioxidant but perhaps more importantly a remarkably potent inhibitor of T NFalpha production.About:
This article is published in Free Radical Biology and Medicine.The article was published on 2000-07-01. It has received 176 citations till now. The article focuses on the topics: Uncaria tomentosa & Ultraviolet light.read more
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Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects.
Arathi R. Setty,Leonard H. Sigal +1 more
TL;DR: This review summarizes the efficacy and toxicities of herbal remedies used in complementary and alternative medical (CAM) therapies for rheumatologic conditions, by elucidating the immune pathways through which these preparations have antiinflammatory and/or immunomodulatory activity and providing a scientific basis for their efficacy.
Journal ArticleDOI
Antioxidant activity by DPPH assay of potential solutions to be applied on bleached teeth
Eugenio Jose Garcia,Tatiane Luiza Cadorin Oldoni,Severino Matias de Alencar,Alessandra Reis,Alessandro Dourado Loguercio,Rosa Helena Miranda Grande +5 more
TL;DR: AAcidS, AAcidG, SodAsS, SodasG and VitE presented the highest antioxidant activity among substances tested in this study, and the DPPH assay provides an easy and rapid way to evaluate potential antioxidants.
Journal ArticleDOI
Natural anti-inflammatory agents for pain relief
TL;DR: Although nonsteroidal medications can be effective, herbs and dietary supplements may offer a safer, and often an effective, alternative treatment for pain relief, especially for long-term use.
Journal ArticleDOI
Biological basis for the use of botanicals in osteoarthritis and rheumatoid arthritis: a review.
TL;DR: This paper reviews the efficacy of some of the common herbs that have a history of human use and their anti-inflammatory or antiarthritic properties and suggests that the extracts of most of these herbs or compounds derived from them may provide a safe and effective adjunctive therapeutic approach for the treatment of OA and RA.
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The effect of freeze-drying and its implications for botanical medicine: a review.
TL;DR: A review of the existing research indicates that freeze‐drying has unanticipated and significant effects on the constituent profiles of medicinal plants that puts into question whether freeze-drying necessarily is the best method to preserve botanical medicines.
References
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Journal ArticleDOI
An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death
Amer A. Beg,David Baltimore +1 more
TL;DR: Reintroduction of RelA into RelA−/− fibroblasts resulted in enhanced survival, demonstrating that the presence ofrelA is required for protection from TNF-α.
Journal ArticleDOI
Infliximab for the treatment of fistulas in patients with Crohn's disease.
Daniel H. Present,Paul Rutgeerts,Stephan R. Targan,Stephen B. Hanauer,Lloyd Mayer,R. A. van Hogezand,Daniel K. Podolsky,Bruce E. Sands,T. Braakman,K. L. Dewoody,Th.F. Schaible,S. J. H. Van Deventer +11 more
TL;DR: Infliximab is an efficacious treatment for fistulas in patients with Crohn's disease and the most common adverse events for patients treated with infliximab were headache, abscess, upper respiratory tract infection, and fatigue.
Journal Article
Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis.
Peter Charles,M J Elliott,Diana Davis,Alison Potter,Joachim R. Kalden,C Antoni,Ferdinand C. Breedveld,Josef S. Smolen,G Eberl,Kim deWoody,Marc Feldmann,Ravinder N. Maini +11 more
TL;DR: In vivo administration of anti-TNF-alpha Ab results in the rapid down-regulation of a spectrum of cytokines, cytokine inhibitors, and acute-phase proteins, consistent with the concept of a cytokine-dependent cytokine cascade.
Journal ArticleDOI
Suppression of nitric oxide synthase and the down-regulation of the activation of NFκB in macrophages by resveratrol
TL;DR: The flavonoids may be of value for inhibiting the enhanced expression of iNOS in inflammation through down‐regulation of NFκB binding activity.
Book
Amazonian ethnobotanical dictionary
James A. Duke,Rodolfo Vasquez +1 more
TL;DR: An Alphabetical Listing of Plants Index of Common Names Medicinal Index Major References is presented, which summarizes the literature on common names of plants and their applications in medicine and health.