Journal ArticleDOI
Causes and management of intestinal failure in children.
Olivier Goulet,Frank M. Ruemmele +1 more
TLDR
Management of patients with intestinal failure requires an early recognition of the condition and the analysis of its risk of irreversibility, and should include therapies adapted to each stage of intestinal failure based on a multidisciplinary approach in centers involving pediatric gastroenterology, parenteral nutrition expertise, home parenTERal nutrition program, pediatric surgery, and liver intestinal transplantation program.About:
This article is published in Gastroenterology.The article was published on 2006-02-01. It has received 344 citations till now. The article focuses on the topics: Intestinal epithelial dysplasia & Parenteral nutrition.read more
Citations
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Journal ArticleDOI
Gut peristalsis is governed by a multitude of cooperating mechanisms.
TL;DR: This review focuses on the role of ICC as slow-wave pacemaker cells and places ICC into the context of other control mechanisms, including control systems intrinsic to smooth muscle cells, and addresses some areas of controversy related to the origin and propagation of pacemaker activity.
Journal ArticleDOI
Improved survival in a multidisciplinary short bowel syndrome program
Biren P. Modi,Monica Langer,Y. Avery Ching,Clarissa Valim,Stephen D. Waterford,Julie Iglesias,Debora Duro,Clifford Lo,Tom Jaksic,Christopher Duggan +9 more
TL;DR: A multidisciplinary approach to intestinal rehabilitation allows for fully integrated care of inpatients and outpatients with SBS by fostering coordination of surgical, medical, and nutritional management.
Journal ArticleDOI
A new intravenous fat emulsion containing soybean oil, medium-chain triglycerides, olive oil, and fish oil: a single-center, double-blind randomized study on efficacy and safety in pediatric patients receiving home parenteral nutrition.
Olivier Goulet,H. Antebi,Claude Wolf,Cécile Talbotec,L.G. Alcindor,Odile Corriol,M. Lamor,Virginie Colomb-Jung +7 more
TL;DR: SMOFlipid 20%, which contains 15% fish oil, was safe and well tolerated, decreased plasma bilirubin, and increased ω-3 FA and α-tocopherol status without changing lipid peroxidation.
Journal ArticleDOI
Very low birth weight preterm infants with surgical short bowel syndrome: incidence, morbidity and mortality, and growth outcomes at 18 to 22 months.
TL;DR: At 18 to 22 months' corrected age, extremely low birth weight infants with short bowel syndrome were more likely to have growth failure than infants without short bowel Syndrome and these infants had growth delay with shorter lengths and smaller head circumferences.
Journal ArticleDOI
Intestinal failure in children: the European view.
Lorenzo D'Antiga,Olivier Goulet +1 more
TL;DR: Better awareness of the risks and benefits of intestinal transplantation have resulted in better patient selection, and ultimately in improved patient survival, hence restricting the indication to transplantation only to patients with nutritional failure and no other chance to survive.
References
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Journal ArticleDOI
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.
Robert S. Wildin,Fred Ramsdell,Jane Peake,Francesca Faravelli,Jean-Laurent Casanova,Neil R. M. Buist,Ephrat Levy-Lahad,Massimo Mazzella,Olivier Goulet,L. Perroni,Franca Dagna Bricarelli,Geoffrey Byrne,Mark McEuen,Sean Proll,Mark Appleby,Mary E. Brunkow +15 more
TL;DR: The human ortholog (FOXP3) of the gene mutated in scurfy mice (Foxp3), in IPEX patients, is sequenced and four non-polymorphic mutations are found, indicating that the mutations may disrupt critical DNA interactions.
Journal ArticleDOI
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
TL;DR: IPEX can be differentiated from other genetic immune disorders by its genetics, clinical presentation, characteristic pattern of pathology, and, except for high IgE, absence of substantial laboratory evidence of immunodeficiency.
Journal ArticleDOI
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis.
TL;DR: The clinical features of IPEX and the structure, function, and known mutations of FOXP3 that provide important insights into its role in maintenance of immune homeostasis are described.
Journal ArticleDOI
Biological actions and therapeutic potential of the glucagon-like peptides.
TL;DR: Inhibitors of DP IV activity, or DP IV-resistant glucagon-like peptide analogues, may be alternative therapeutic approaches for treatment of human diseases.
Journal ArticleDOI
Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon
Palle Jeppesen,Bolette Hartmann,Jesper Thulesen,Jesper Graff,Jette Lohmann,Birthe Stenbæk Hansen,Flemming Tofteng,Steen Seier Poulsen,Jan Lysgaard Madsen,Jens J. Holst,Per Brøbech Mortensen +10 more
TL;DR: Treatment with GLP-2 improves intestinal absorption and nutritional status in short-bowel patients with impaired postprandial GLp-2 secretion in whom the terminal ileum and the colon have been resected.
Related Papers (5)
Natural history of pediatric intestinal failure: initial report from the Pediatric Intestinal Failure Consortium.
Robert H. Squires,Christopher Duggan,Daniel H. Teitelbaum,Paul W. Wales,Jane Balint,Robert S. Venick,Sue Rhee,Debra L. Sudan,David F. Mercer,J. Andres Martinez,Beth A. Carter,Jason S. Soden,Simon Horslen,Jeffrey A. Rudolph,Samuel A. Kocoshis,Riccardo A. Superina,Sharon Lawlor,Tamara Haller,Marcia Kurs-Lasky,Steven H. Belle +19 more