Journal ArticleDOI
Changes in whole blood viscosity at low shear rates correlate with intravascular volume changes during hemodialysis.
Reads0
Chats0
TLDR
The results suggest that the WBV parameter may hold additional information beyond hemoconcentration in patients with end-stage renal disease and further research is needed to evaluate the relationship between low-shear WBV surges and increased morbidity in the patient population with ESRD.Abstract:
Background:Elevated blood viscosity has been shown to be independently correlated with cardiovascular risk factors and associated with increased risk of major cardiovascular events, including deathread more
Citations
More filters
Journal ArticleDOI
Effects of Volume Overload and Current Techniques for the Assessment of Fluid Status in Patients with Renal Disease.
TL;DR: This review aims to evaluate volume overload, its effects on patients with renal diseases and current methodologies measuring volume status in the body, which includes biomarkers, ultrasonography, relative blood volume monitoring, bioimpedance, echocardiography, pulmonary artery catheterization, esophageal and/or suprasternal Doppler, and blood viscosity.
Journal ArticleDOI
The passage of a hemodialysis filter affects hemorheology, red cell shape, and platelet aggregation.
TL;DR: It is concluded that the passage of a hemodialysis filter induced RBC shape changes, increased the hematocrit, whole blood and plasma viscosity, decreased RBC aggregation, and affected platelet aggregation.
Journal ArticleDOI
Changes in whole blood viscosity during hemodialysis and mortality in patients with end-stage renal disease.
TL;DR: Data showed that a high degree of change in WBV at variable shear rates during hemodialysis might impact overall survival in patients with end-stage kidney disease, and large-scale studies to evaluate the relationship of WBV with overall mortality and atherosclerotic mortality will be needed.
Journal ArticleDOI
Serum nitric oxide level correlates with serum brain natriuretic peptide and whole blood viscosity in hemodialysis patients.
TL;DR: WBV is linked to an imbalance in serum vasoactive substances in hemodialysis patients and can cause significant hemodynamic disturbance and ANP levels have a negative correlation with pre-dialytic WBV.
Journal ArticleDOI
Improvement and application of an acute blood stasis rat model aligned with the 3Rs (reduction, refinement and replacement) of humane animal experimentation
TL;DR: A stable, reproducible, and improved acute blood stasis rat model, which could be applied to screen drugs for promoting blood circulation and eliminating bloodStasis, is presented and is associated with the highest WBV value.
References
More filters
Journal ArticleDOI
Clinical epidemiology of cardiovascular disease in chronic renal disease.
Journal ArticleDOI
The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin.
Anatole Besarab,W K Bolton,J K Browne,Joan C. Egrie,Allen R. Nissenson,D M Okamoto,Steve J. Schwab,David A. Goodkin +7 more
TL;DR: In patients with clinically evident congestive heart failure or ischemic heart disease who are receiving hemodialysis, administration of epoetin to raise their hematocrit to 42 percent is not recommended.
Journal ArticleDOI
Prediction of blood volume in normal human adults.
Journal ArticleDOI
Blood rheology and hemodynamics.
TL;DR: Blood rheology has been reported to be altered in various physiopathological processes: Alterations of hematocrit significantly contribute to hemorheological variations in diseases and in certain extreme physiological conditions, and RBC deformability is sensitive to local and general homeostasis.
Journal Article
Endothelial dysfunction : Mechanisms of hypertension: Cells, hormones, and the kidney
TL;DR: Mechanisms that participate in the reduced vasodilatory responses in endothelial dysfunction include reduced nitric oxide generation, oxidative excess, and reduced production of hyper-polarizing factor.