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Book ChapterDOI

Choline Metabolism in Insects

TLDR
The chapter considers only the choline-containing lipids, but in almost all cases a fairly complete analysis of the different phospholipid types has been carried out, and this may be obtained by consulting the appropriate reference.
Abstract
Publisher Summary The importance of choline in the metabolic processes of vertebrates has been established for many years. Nutritional studies with animals fed on low protein and high fat regimes have demonstrated that large amounts of choline are required in the diet if normal growth is to be maintained and fatty infiltration of the liver prevented. In insects, various aspects of choline metabolism have been looked at in differing detail. The cholinergic system has received a great deal of attention because of its importance in relation to the mode of action of organophosphorus and carbamate insecticides. The composition of insect phospholipids has been analyzed and results from a large number of species have accumulated over the past few years. The chapter considers only the choline-containing lipids, but in almost all cases a fairly complete analysis of the different phospholipid types has been carried out, and this may be obtained by consulting the appropriate reference. A number of studies have been made following the change of phospholipid pattern during development, but little has been achieved in understanding the metabolic role of the phospholipid.

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Citations
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Journal ArticleDOI

Histochemistry of putative transmitter substances in the insect brain

N Klemm
TL;DR: The present review attempts to evaluate the available histochemical data bearing on the possible transmitter roles of various candidate compounds in these animals and to call attention to cases where this has happened.
Journal ArticleDOI

Concentrations of some putative neurotransmitters in the CNS of quick-frozen insects

B.S. Clarke, +1 more
- 01 Jan 1982 - 
TL;DR: The CNS of adult houseflies, locusts, fleshflies and larval cotton leafworm had comparatively high concentrations of alanine, GABA, aspartate, octopamine, dopamine, noradrenaline and glutamate (glutamine).
References
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Journal ArticleDOI

The function of cytidine coenzymes in the biosynthesis of phospholipides.

TL;DR: The ratio of P32 to Cl4 in the product was closely similar to that of the labeled P-choline, suggesting incorporation of both phosphorus and choline as an intact unit into a phospholipide, presumably lecithin.
Journal ArticleDOI

Methyl transfering enzyme system of microsomes in the biosynthesis of lecithin (phosphatidylcholine)

TL;DR: The incorporation of the first methyl group is found to be the rate limiting step in choline biosynthesis, and the choline-synthesizing enzyme system is found in several tissues of the rat and in the liver of 8 different animal species investigated.
Journal ArticleDOI

The Quantitative Nutritional Requirements of Drosophila Melanogaster

TL;DR: The minimal nutritional requirements of Drosophila larvae are shown to be considerably less than those of other aseptically cultured insects and, as far as the vitamins are concerned, only broadly related to the amounts found in yeast.
Journal ArticleDOI

The metabolism of sphingomyelin. I. Purification and properties of a sphingomyelin-cleaving enzyme from rat liver tissue.

TL;DR: The most highly purified enzyme preparations catalyzed the hydrolysis of sphingomyelin, whereas lecithin and phosphatidylethanolamine were unaffected and the products of the reaction were identified as phosphorylcholine and ceramide.
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