Chronic Cellular Dehydration in the Aged Patient
Patrick Ritz,Centre-Auvergne +1 more
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TLDR
Water spaces and cellular hydration in adults, healthy and diseased aged patients are compared and Diseased elderly persons display reduced ICW and expanded ECW is suggested.Abstract:
BACKGROUND As a reduction of water spaces is expected in the elderly because of fat-free mass loss, disease is often associated with increased hydration. The present study compared water spaces and cellular hydration in adults, healthy and diseased aged patients. METHODS An open study was conducted in 6 geriatric wards and a nutrition laboratory involving 85 aged diseased persons, 68 healthy elderly adults, and 35 adults. Total body water (TBW, H(2)(18)O dilution), extracellular water (ECW, Bromide dilution), and fat-free mass (FFM, body density and Siri's equation) were measured directly whereas intracellular water (ICW = TBW - ECW) and body cell mass (FFM - ECW) were obtained by calculations. RESULTS FFM, TBW, and ICW were higher in adults than in the 2 other groups and in the elderly than in aged patients. ECW was higher in aged patients than in healthy elderly participants. The proportion of TBW made of ECW or ICW was the same in adults and in healthy elderly persons. A higher proportion of TBW was composed of ECW, and a lower proportion of TBW was composed of ICW, in diseased patients compared with the 2 other groups. The proportion of ICW in body cell mass was also lower in diseased patients. CONCLUSIONS Diseased elderly persons display reduced ICW and expanded ECW. A cellular dehydration is suggested.read more
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Patent
Device and method for monitoring body fluid and electrolyte disorders
TL;DR: In this paper, the authors presented a device for measuring a body-tissue water content metric as a fraction of the fat-free tissue content of a patient using optical spectrophotometry.
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Clinical symptoms, signs and tests for identification of impending and current water‐loss dehydration in older people
Lee Hooper,Asmaa Abdelhamid,Natalie J Attreed,Wayne W. Campbell,Adam M. Channell,Philippe Chassagne,Kennith Culp,Stephen J. Fletcher,Matthew B. Fortes,Nigel Fuller,Phyllis Gaspar,Daniel Gilbert,Adam C. Heathcote,M W Kafri,Fumiko Kajii,Gregor Lindner,Gary W. Mack,Janet C. Mentes,Paolo Merlani,Rowan A. Needham,Marcel G.M. Olde Rikkert,Andreas Perren,James S. Powers,Sheila C. Ranson,Patrick Ritz,Anne M Rowat,Fredrik Sjöstrand,Alexandra C Smith,Jodi J. D. Stookey,Nancy A. Stotts,David R. Thomas,Angela Vivanti,Bonnie J. Wakefield,Nana Waldréus,Neil P. Walsh,Sean Ward,John F. Potter,Paul R. Hunter +37 more
TL;DR: To determine the diagnostic accuracy of state (one time), minimally invasive clinical symptoms, signs and tests to be used as screening tests for detecting water-loss dehydration in older people by systematically reviewing studies that have measured a reference standard and at least one index test in people aged 65 years and over.
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Extracellular Water May Mask Actual Muscle Atrophy During Aging
Yosuke Yamada,Yosuke Yamada,Yosuke Yamada,Dale A. Schoeller,Eitaro Nakamura,Taketoshi Morimoto,Misaka Kimura,Shingo Oda +7 more
TL;DR: The results suggest that the expansion of ECW relative to ICW and the LV masked actual muscle cell atrophy with aging.
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Accuracy of segmental multi-frequency bioelectrical impedance analysis for assessing whole-body and appendicular fat mass and lean soft tissue mass in frail women aged 75 years and older.
TL;DR: SMF-BIA had acceptable accuracy for the estimation of whole-body and appendicular FM and LM in frail older women, although SMF- BIA underestimated LM and overestimated FM relative to DXA.
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