Circadian distribution of sleep phases after major abdominal surgery
Reads0
Chats0
TLDR
Patients have significantly increased REM sleep, LS, and reduced time awake during the daytime period after surgery compared with before surgery, suggesting disturbances in the circadian regulation of the sleep-wake cycle may be involved in the development of postoperative sleep disturbances.Abstract:
Background It is believed that the severely disturbed night-time sleep architecture after surgery is associated with increased cardiovascular morbidity with rebound of rapid eye movement (REM). The daytime sleep pattern of patients after major general surgery has not been investigated before. We decided to study the circadian distribution of sleep phases before and after surgery. Methods Eleven patients undergoing elective major abdominal surgery were included in the study. Continuous ambulatory polysomnographic monitoring was made 24 h before surgery and 36 h after surgery, thus including two nights after operation. Sleep was scored independently by two blinded observers and the recordings were reported as awake, light sleep (LS, stages I and II), slow wave sleep (SWS, stages III and IV), and REM sleep. Results There was significantly increased REM sleep ( P =0.046), LS ( P =0.020), and reduced time awake ( P =0.016) in the postoperative daytime period compared with the preoperative daytime period. Five patients had REM sleep during the daytime after surgery. Three of these patients did not have REM sleep during the preceding postoperative night. There was significantly reduced night-time REM sleep for two nights after surgery compared with before surgery ( P =0.001). Conclusions Patients have significantly increased REM sleep, LS, and reduced time awake during the daytime period after surgery compared with before surgery. Disturbances in the circadian regulation of the sleep–wake cycle may be involved in the development of postoperative sleep disturbances.read more
Citations
More filters
Journal ArticleDOI
New insights into the pathophysiology of postoperative cognitive dysfunction
TL;DR: It is concluded that the pathogenesis of POCD is multifactorial and future studies should focus on evaluating the role of postoperative sleep disturbances, inflammatory stress responses, pain and environmental factors.
Journal ArticleDOI
Identification of Patients at Risk for Postoperative Respiratory Complications Using a Preoperative Obstructive Sleep Apnea Screening Tool and Postanesthesia Care Assessment
TL;DR: Combination of an obstructive sleep apnea screening tool preoperatively (SACS) and recurrent PACU respiratory events was associated with a higher oxygen desaturation index and postoperative respiratory complications.
Journal ArticleDOI
Independent Predictors and Outcomes of Unanticipated Early Postoperative Tracheal Intubation after Nonemergent, Noncardiac Surgery
Satya Krishna Ramachandran,Olubukola O. Nafiu,Amir A. Ghaferi,Kevin K. Tremper,Amy Shanks,Sachin Kheterpal +5 more
TL;DR: One half of unanticipated tracheal intubations in a period of 30 days occurred within the first 3 days after nonemergent, noncardiac surgery and were independently associated with a 9-fold increase in mortality.
Journal ArticleDOI
Postoperative changes in sleep-disordered breathing and sleep architecture in patients with obstructive sleep apnea
TL;DR: Postoperatively, sleep architecture was disturbed and AHI was increased in both OSA and non-OSA patients and breathing disturbances during sleep were greatest on postoperative N3.
Journal ArticleDOI
Factors Associated with Postoperative Exacerbation of Sleep-disordered Breathing
TL;DR: Patients with a higher preoperative AHI were predicted to have a higher postoperatively AHI and slow wave sleep percentage was inversely associated with postoperative A HI and central apnea index.
References
More filters
Journal ArticleDOI
Sleep disturbances after non-cardiac surgery
TL;DR: After major non-cardiac surgery sleep pattern is usually disturbed with initial suppression of rapid eye movement sleep with a subsequent rebound during the first post-operative week, and the sleep disturbances seem to be related to the magnitude of trauma.
Journal ArticleDOI
Sleep in herniorrhaphy patients
TL;DR: The nocturnal sleep patterns of elective herniorrhaphy patients showed a dramatic loss of REM sleep and stages III and IV and major increases in time awake and drowsy for the first 2 postoperative nights, with a gradual return toward normal sleep over the hospitalization period.
Journal ArticleDOI
All-night polygraphic studies of nocturnal angina pectoris.
Satoru Murao,Kenichi Harumi,Soichi Katayama,Saburo Mashima,Katsuro Shimomura,Masahiro Murayama,Hiroshi Matsuo,Hideo Yamamoto,Ryoko Kato,Chia-Maou Chen +9 more
TL;DR: In 12 patients with nocturnal angina pectoris, all-night continuous polygraphic recordings were made, and ECG and heart rate during sleep disclosed that the attacks were not likely to be induced by REM-associated increase of heart rate and, in individual episodes, heart rate increase did not precede the ST, T changes.
Journal ArticleDOI
Sleep in the Surgical Intensive Care Unit: Continuous Polygraphic Recording of Sleep in Nine Patients Receiving Postoperative Care
Jonas Aurell,Dan Elmqvist +1 more
TL;DR: In this article, sleep was studied in nine patients for two to four days after major non-cardiac surgery by continuous polygraphic recording of electroencephalogram, electrooculogram, and electromyogram.
Journal ArticleDOI
Disturbances in Melatonin, Cortisol and Core Body Temperature Rhythms after Major Surgery
TL;DR: Disturbances in three circadian markers after major surgery were found, including melatonin, cortisol and core body temperature rhythms, which were found to play a role in the development of postoperative sleep disturbances, fatigue, cognitive dysfunction and cardiovascular morbidity.