Journal ArticleDOI
Collagen-carbon nanotube composite materials as scaffolds in tissue engineering.
Rebecca A. MacDonald,Brendan F. Laurenzi,Gunaranjan Viswanathan,Pulickel M. Ajayan,Jan P. Stegemann +4 more
TLDR
Collagen-CNT composite matrices may have utility as scaffolds in tissue engineering, or as components of biosensors or other medical devices, and Scanning electron microscopy showed physical interactions between CNT and collagen matrix.Abstract:
Carbon nanotubes (CNT) are attractive for use in fiber-reinforced composite materials due to their very high aspect ratio, combined with outstanding mechanical and electrical properties. Composite materials comprising a collagen matrix with embedded CNT were prepared by mixing solubilized Type I collagen with solutions of carboxylated single-walled carbon nanotubes (SWNT) at concentrations of 0, 0.2, 0.4, 0.8, and 2.0 weight percent. Living smooth muscle cells were incorporated at the time of collagen gelation to produce cell-seeded collagen-CNT composite matrices. Constructs containing 2.0 wt % CNT exhibited delayed gel compaction, relative to lower concentrations that compacted at the same rate as pure collagen controls. Cell viability in all constructs was consistently above 85% at both Day 3 and Day 7, whereas cell number in CNT-containing constructs was lower than in control constructs at Day 3, though statistically unchanged by Day 7. Scanning electron microscopy showed physical interactions between CNT and collagen matrix. Raman spectroscopy confirmed the presence of CNT at the expected diameter (0.85-1.30 nm), but did not indicate strong molecular interactions between the collagen and CNT components. Such collagen-CNT composite matrices may have utility as scaffolds in tissue engineering, or as components of biosensors or other medical devices.read more
Citations
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Journal ArticleDOI
Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy
Journal ArticleDOI
Carbon nanotube applications for tissue engineering.
TL;DR: Carbon nanotubes may play an integral role as unique biomaterial for creating and monitoring engineered tissue as well as imparting novel properties such as electrical conductivity into the scaffolds may aid in directing cell growth.
Journal ArticleDOI
Carbon nanotubes: properties, synthesis, purification, and medical applications
Ali Eatemadi,Hadis Daraee,Hamzeh Karimkhanloo,Mohammad Kouhi,Nosratollah Zarghami,Abolfazl Akbarzadeh,Mozhgan Abasi,Younes Hanifehpour,Sang Woo Joo +8 more
TL;DR: The strength and flexibility of carbon nanotubes make them of potential use in controlling other nanoscale structures, which suggests they will have a significant role in nanotechnology engineering.
Journal ArticleDOI
Electrophoretic deposition of carbon nanotubes
Aldo R. Boccaccini,Johann Cho,Judith A. Roether,B. J. C. Thomas,E. Jane Minay,Milo S. P. Shaffer +5 more
TL;DR: An up-to-date comprehensive overview of current research progress in the field of electrophoretic deposition of carbon nanotubes (CNTs) can be found in this article.
Journal ArticleDOI
Bone cell proliferation on carbon nanotubes
TL;DR: There was a dramatic change in cell morphology in osteoblasts cultured on MWNTs, which correlated with changes in plasma membrane functions, and CNTs carrying neutral electric charge sustained the highest cell growth and production of plate-shaped crystals.
References
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Journal ArticleDOI
Advances in the science and technology of carbon nanotubes and their composites: a review
TL;DR: A review of recent advances in carbon nanotubes and their composites can be found in this article, where the authors examine the research work reported in the literature on the structure and processing of carbon Nanotubes.
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Carbon Nanotubes: Synthesis, Integration, and Properties
TL;DR: In this paper, the van der Waals self-assembly forces and applied electric fields are used to control the growth direction of carbon nanotubes in a patterned growth approach.
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Functionalized Carbon Nanotubes: Properties and Applications
TL;DR: Representative results concerning the solubility, dispersion, defunctionalization, and optical properties of the functionalized carbon nanotubes are presented.
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Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.