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Collision of the COVID-19 and Addiction Epidemics.

Nora D. Volkow
- 02 Apr 2020 - 
- Vol. 173, Iss: 1, pp 61-62
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TLDR
The risks of the collision of the COVID-19 and addiction epidemics are described, which could put at risk those who have opioid use disorder and methamphetamine use disorder.
Abstract
People with substance use disorder may be especially susceptible to COVID-19, and compromised lung function from COVID-19 could also put at risk those who have opioid use disorder and methamphetamine use disorder. This commentary describes the risks of the collision of the COVID-19 and addiction epidemics.

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Citations
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Comparing actual and forecasted numbers of unique patients dispensed select medications for opioid use disorder, opioid overdose reversal, and mental health, during the COVID-19 pandemic, United States, January 2019 to May 2020.

TL;DR: In this article, the authors used the IQVIA Total Patient Tracker data to calculate U.S. monthly numbers of unique patients dispensed buprenorphine, extended-release (ER) intramuscular naltrexone, naloxone, selective serotonin or serotonin-norepinephrine reuptake inhibitors, benzodiazepines, and for comparison, HMG-CoA reductase inhibitors (statins) and angiotensin receptor blockers (ARBs) between January 2019-May 2020).
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COVID-19 and overdose prevention: Challenges and opportunities for clinical practice in housing settings.

TL;DR: Modifications to the OUD care continuum included modified supervised injection spaces to adhere to physical distancing, the use of personal protective equipment for overdose response, virtual platforms for clinical encounters, writing longer prescriptions, and providing take-home doses to promote opioid agonist treatment retention.
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Increased flexibility in methadone take-home scheduling during the COVID-19 pandemic: Should this practice be incorporated into routine clinical care?

TL;DR: This commentary underscores the importance of ensuring a sufficient quantity of methadone take-home doses for patients to maximize their adherence to Methadone maintenance treatment (MMT) during government-imposed lockdown restrictions and social distancing measures designed to curtail the spread of SARS-CoV-2.
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Alcohol and substance use in pregnancy during the COVID-19 pandemic

TL;DR: For example, the authors found that higher depression symptoms and financial difficulties were associated with more tobacco use, cannabis use, and substance co-use during the COVID-19 pandemic.
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COVID-19, mental health, and opioid use disorder: Old and new public health crises intertwine.

TL;DR: While the United States has acted to improve access to treatment for mental health and opioid use, research will be needed to understand the effectiveness of new policies in the context of COVID-19.
References
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Journal ArticleDOI

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine.

TL;DR: It is shown that compared with smoke exposure, mice receiving ENDS vapor for 4 months failed to develop pulmonary inflammation or emphysema, and ENDS exposure, independent of nicotine, altered lung lipid homeostasis in alveolar macrophages and epithelial cells.
Journal ArticleDOI

Predictors of Opioid-Related Death During Methadone Therapy

TL;DR: A population-based, nested case-control study linking healthcare and coroner's records in Ontario, Canada, from January 31, 1994 to December 31, 2010, found psychotropic drug use is associated with opioid-related death in patients receiving methadone, and mindfulness of these factors may reduce the risk of death among Methadone recipients.
Journal ArticleDOI

Clinical Characteristics and Outcome of Methamphetamine-Associated Pulmonary Arterial Hypertension and Dilated Cardiomyopathy

TL;DR: Male sex, hypertension, and alcoholism were strongly associated with MA-CMP, whereas female sex and other unknown factors may influence development of MA-PAH.
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