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Journal ArticleDOI

Complications of Iliac Crest Bone Graft Harvesting

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TLDR
In a retrospective review of 414 consecutive cases of iliac crest bone graft procedures performed at Brooke Army Medical Center from 1983 to 1993, 41 (10%) minor and 24 (5.8%) major complications were identified.
Abstract: 
Autologous bone grafts harvested from the iliac crest are commonly used in reconstructive orthopaedic surgery. Autologous bone is used to help promote bone healing in fractures and to provide structural support for reconstructive surgery. The results of autologous bone grafting are more predictable than the use of xenografts, cadaveric allografts, or synthetic bone substitutes because autologous bone grafts provide osteoinductive and osteoconductive properties, are not immunogenic, and are usually well incorporated into the graft site. In a retrospective review of 414 consecutive cases of iliac crest bone graft procedures performed at Brooke Army Medical Center from 1983 to 1993, 41 (10%) minor and 24 (5.8%) major complications were identified. Minor complications included superficial infections, superficial seromas, and minor hematomas. Major complications included herniation of abdominal contents through massive bone graft donor sites, vascular injuries, deep infections at the donor site, neurologic injuries, deep hematoma formation requiring surgical intervention, and iliac wing fractures. Harvesting of iliac crest bone graft can be associated with significant morbidity. However, with adequate preoperative planning and proper surgical technique, the incidence of these complications can be reduced.

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Citations
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Bone substitutes: an update.

TL;DR: An overview of bone grafts and graft substitutes available for clinical applications is presented and osteoinductive growth factors, osteogenic cells, and an osteoconductive scaffold are provided.
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Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion.

TL;DR: A large percentage of patients report chronic donor site pain after anterior ICBG donation, even when only a single-level ACDF procedure is performed, and long-term functional impairment can also be significant.
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Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial: 2002 Volvo Award in clinical studies.

TL;DR: This pilot study is the first with at least 1 year of follow-up evaluation to demonstrate successful posterolateral spine fusion using a BMP-based bone graft substitute, with radiographs and CT scans as the determinant.
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Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review.

TL;DR: The use of RIA device as harvesting method seems a promising alternative with a low complication rate and the rates of certain complications were found to significantly differ when anterior or posterior iliac crest was used.
References
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Journal ArticleDOI

Morbidity at bone graft donor sites.

TL;DR: A review of the medical records of 239 patients with 243 autogenous bone grafts was undertaken to document the morbidity at the donor sites, finding that there was a much higher complication rate if the incision used for the surgery was also the sameincision used to harvest the bone graft.
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Harvesting Autogenous Iliac Bone Grafts: A Review of Complications and Techniques

TL;DR: Autogenous bone grafts from the ilium are frequently harvested for purposes of bone union and/or stability, but awareness of the anatomy and complications may aid in planning the approach and minimizing the risks.
Journal ArticleDOI

Donor site pain from the ilium. A complication of lumbar spine fusion

TL;DR: Chronic pain at the donor site was reported by 25% of 290 patients who had undergone anterior lumbar spine fusion for low back pain and patients with a clinically unsatisfactory result from the spine fusion also had a significantly higher prevalence of donor site pain.
Journal ArticleDOI

Donor-site morbidity after harvesting rib and iliac bone.

TL;DR: Morbidity following 104 bone graft harvesting operations in 72 patients is documented and early morbidity of iliac donor sites was found to be far greater than that of rib donor sites.
Journal ArticleDOI

Current Approaches to Experimental Bone Grafting

TL;DR: Current areas of research in the realm of experimental grafting are reviewed, including the current understanding of materials that manifest osteogenic, osteoinductive, or osteoconductive properties.
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