Comprehensive analysis of etiology on the prognosis of urethral strictures
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It is demonstrated that etiology of urethral strictures may play a vital role for the overall prognosis of urethroplasty and the "cause-effect" relationship between etiology and prognosis is evaluated.Abstract:
Introduction: Urethral strictures remain a reconstructive dilemma, due to high incidence of recurrence and less than satisfactory outcomes. Even experienced surgeons following strict surgical principles have not achieved optimal results, leading us to think whether the etiology of strictures dictate the outcome . We evaluated this “cause-effect” relationship highlighting the significance of the etiology on the overall prognosis of urethral strictures. Materials and Methods: A total of 302 males with urethral strictures were assessed (both retrospectively and prospectively) over a period of ten years. The preoperative evaluation was performed by retrograde urethrogram, urethrosonogram, and uroflowmetry and categorized, based on etiology: a) as post traumatic, b) post infective, c) iatrogenic or d) unknown. Traumatic strictures were subjected to pelvic X-ray and sub-categorized into grades A, B and C, following the TILE classification. Patients were operated; with tunica albuginea urethroplasty for anterior strictures and U shape prostato-bulbar anastomosis for posterior strictures. Results: Traumatic strictures accounted for 54% of cases. 127 of the 302 patients were treated using Tunica Albuginea Urethroplasty, while U shaped Prostatobulbar Anastomosis was performed on others. Post traumatic strictures had best outcome whereas post infective strictures had the worse outcome. Among strictures following pelvic fractures, TILE grades A and B had a better post operative course as compared to TILE C. Overall complication rate was 13.24%. Conclusion: Our study demonstrated that etiology of urethral strictures may play a vital role for the overall prognosis of urethral strictures. Clinical Urologyread more
Citations
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Simple urethral dilatation, endoscopic urethrotomy, and urethroplasty for urethral stricture disease in adult men
TL;DR: To determine which is the best surgical treatment for male urethral stricture disease taking into account relative efficacy, adverse event rates and cost-effectiveness, two randomised trials were identified.
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A geographic analysis of male urethral stricture aetiology and location
Daniel Stein,D. Joseph Thum,Guido Barbagli,Sanjay Kulkarni,Salvatore Sansalone,Ashish Pardeshi,Chris M. Gonzalez +6 more
TL;DR: A multi‐centred series is provided to compare aetiologic incidence between differing regional populations of urethral stricture disease.
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Urethral reconstruction using buccal mucosa or penile skin grafts: systematic review and meta-analysis.
TL;DR: Success of UR using BMG is significantly better compared to PSG, and results might be seriously biased by a longer follow-up duration and stricture length for PSG compared to BMG.
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Epidemiology of urethral strictures.
TL;DR: A comprehensive review of urethral stricture disease based on available published case series, identified gaps in knowledge of this disease, and recommend future directions for research are performed.
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Changing trends in the causes and management of male urethral stricture disease in China: an observational descriptive study from 13 centres.
Yuemin Xu,Lujie Song,Kun-Jie Wang,Jian Lin,Guang Sun,Zhong-Jin Yue,Hai Jiang,Yu-Xi Shan,Shao-Xing Zhu,Yu-Jie Wang,Zhi-ming Liu,Zhen-Hua Li,Zhong-Hua Liu,Qing-Ke Chen,Minkai Xie +14 more
TL;DR: To determine whether there have been any changes in the causes and management of urethral strictures in China, a large number of cases have been reported in the past five years.
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Etiology of urethral stricture disease in the 21st century.
Nicolaas Lumen,Piet Hoebeke,Pieter Willemsen,Bart De Troyer,Ronny Pieters,Willem Oosterlinck +5 more
TL;DR: The current etiology of urethral stricture disease in the developed world and whether there are any differences in etiology by patient age and stricture site is determined and significantly different in younger vs older patients and among stricture sites.
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Incidence of Urethral Stricture After Primary Treatment for Prostate Cancer: Data From CaPSURE
Sean P. Elliott,Maxwell V. Meng,Eric P. Elkin,Jack W. McAninch,Janeen DuChane,Peter R. Carroll,CaPSURE Investigators +6 more
TL;DR: Stricture after radical prostatectomy occurred within the first 24 months, whereas onset was delayed after radiation, and the risk of urethral stricture treatment after prostate cancer therapy is 1.1% to 8.4% depending on cancer treatment type.