Journal ArticleDOI
Computerized tomographic scan findings in patients with autistic behavior.
TLDR
An analysis of the computerized tomography scans of 17 patients with autistic behavior found that it was not possible to discern a singular abnormal pattern, the abnormalities appearing consequent to a variety of disease processes of the CNS.Abstract:
• An analysis of the computerized tomography scans of 17 patients with autistic behavior was carried out by investigators independent from those selecting the subjects. Mild abnormalities of the ventricular system were noted in several scans (increased size, altered left/right relation of lateral ventricles), and in three scans major hydrocephalus and circumscribed lesions of the parenchyma were seen. It was not possible to discern a singular abnormal pattern, the abnormalities appearing consequent to a variety of disease processes of the CNS.read more
Citations
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Practice parameter: Screening and diagnosis of autism Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society
Pauline A. Filipek,Pasquale J. Accardo,Stephen Ashwal,Grace T. Baranek,Edwin H. Cook,Geraldine Dawson,Barry Gordon,Judith S. Gravel,Chris Plauché Johnson,Ronald J. Kallen,Susan E. Levy,Nancy J. Minshew,Sally J Ozonoff,Barry M. Prizant,Isabelle Rapin,Sally J. Rogers,Wendy L. Stone,Stuart W. Teplin,Roberto Tuchman,Fred R. Volkmar +19 more
TL;DR: This approach requires a dual process: 1) routine developmental surveillance and screening specifically for autism to be performed on all children to first identify those atrisk for any type of atypical development, and to identify those specifically at risk for autism.
Journal ArticleDOI
Hypoplasia of Cerebellar Vermal Lobules VI and VII in Autism
TL;DR: In patients with autism, neocerebellar abnormality may directly impair cognitive functions that some investigators have attributed to the neoceebellum; may indirectly affect the development and functioning of one or more systems involved in cognitive, sensory, autonomic, and motor activities.
Journal ArticleDOI
The screening and diagnosis of autistic spectrum disorders
Pauline A. Filipek,Pasquale J. Accardo,Grace T. Baranek,Edwin H. Cook,Geraldine Dawson,Barry Gordon,Judith S. Gravel,Chris Plauché Johnson,Ronald J. Kallen,Susan E. Levy,Nancy J. Minshew,Barry M. Prizant,Isabelle Rapin,Sally J. Rogers,Wendy L. Stone,Stuart W. Teplin,Roberto Tuchman,Fred R. Volkmar +17 more
TL;DR: Specific detailed recommendations for each level have been established in this document, which are intended to improve the rate of early suspicion and diagnosis of, and therefore early intervention for, autism.
Journal ArticleDOI
Autism: Towards an Integration of Clinical, Genetic, Neuropsychological, and Neurobiological Perspectives
TL;DR: A partial integration of the causal processes leading to autism requires an integration across different levels of enquiry, and provides a useful strategy for identifying key research questions, the limitations of existing hypotheses, and future research directions that are likely to prove fruitful.
Journal ArticleDOI
Neuropsychologic functioning in autism: profile of a complex information processing disorder.
TL;DR: The neuropsychologic profile in 33 rigorously diagnosed autistic individuals was defined by impairments in skilled motor, complex memory, complex language, and reasoning domains, and by intact or superior performance in the attention, simple memory, simplelanguage, and visual-spatial domains.
References
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A Neurological Model for Childhood Autism
TL;DR: The behavioral and motor disturbances in childhood autism are analyzed to propose that the syndrome results from dysfunction in a system of bilateral neural structures that includes the ring of mesolimbic cortex located in the mesial frontal and temporal lobes, the neostriatum, and the anterior and medial nuclear groups of the thalamus.
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Measurements of the normal ventricular system and hemispheric sulci of 100 adults with computed tomography
TL;DR: There was a statistically significant increase of all cerebral parameters with age, and the cella media index showed a correspondingly small decrease with age.
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Pneumographic findings in the infantile autism syndrome. A correlation with temporal lobe disease.
TL;DR: It is suggested that medial temporal lobe dysfunction may be a major factor in the pathogenesis of the syndrome of infantile autism.
Journal ArticleDOI
Frontal ventricular dimensions on normal computed tomography.
TL;DR: The computerized axial tomographic examinations of 200 normal patients and volunteers and a dimension representing the distance between the outer borders of the lateral ventricles was made, the cerebroventricular index seems to be a reliable indicator of ventricular size.